"Macrocyclic Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.
| Descriptor ID |
D047028
|
| MeSH Number(s) |
D04.345
|
| Concept/Terms |
Macrocyclic Compounds- Macrocyclic Compounds
- Compounds, Macrocyclic
- Macrocycle Compounds
- Compounds, Macrocycle
|
Below are MeSH descriptors whose meaning is more general than "Macrocyclic Compounds".
Below are MeSH descriptors whose meaning is more specific than "Macrocyclic Compounds".
This graph shows the total number of publications written about "Macrocyclic Compounds" by people in this website by year, and whether "Macrocyclic Compounds" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Macrocyclic Compounds" by people in Profiles.
-
Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer. Cancer Lett. 2022 11 28; 549:215915.
-
Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing. ACS Synth Biol. 2020 07 17; 9(7):1882-1896.
-
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection. N Engl J Med. 2017 06 01; 376(22):2134-2146.
-
Moderate endoplasmic reticulum stress activates a PERK and p38-dependent apoptosis. Cell Stress Chaperones. 2017 01; 22(1):43-54.
-
Regio- and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Macrocyclic Diversity. ACS Comb Sci. 2015 Aug 10; 17(8):437-41.
-
Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox. Org Lett. 2015 Feb 06; 17(3):468-71.
-
Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014 Apr 24; 370(17):1594-603.
-
Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group. J Am Chem Soc. 2011 Jun 22; 133(24):9196-9.
-
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. J Am Chem Soc. 2010 Dec 01; 132(47):16962-76.
-
Encapsulation and selective recognition of sulfate anion in an azamacrocycle in water. Chem Commun (Camb). 2010 Sep 07; 46(33):6084-6.