"Drug Discovery" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of finding chemicals for potential therapeutic use.
| Descriptor ID |
D055808
|
| MeSH Number(s) |
E05.295 H01.158.703.007.675 H01.181.466.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Discovery".
Below are MeSH descriptors whose meaning is more specific than "Drug Discovery".
This graph shows the total number of publications written about "Drug Discovery" by people in this website by year, and whether "Drug Discovery" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 4 | 5 | 9 |
| 2011 | 3 | 3 | 6 |
| 2012 | 2 | 1 | 3 |
| 2013 | 4 | 4 | 8 |
| 2014 | 3 | 3 | 6 |
| 2015 | 4 | 5 | 9 |
| 2016 | 2 | 6 | 8 |
| 2017 | 3 | 3 | 6 |
| 2018 | 3 | 8 | 11 |
| 2019 | 2 | 6 | 8 |
| 2020 | 4 | 4 | 8 |
| 2021 | 2 | 5 | 7 |
| 2022 | 3 | 4 | 7 |
| 2023 | 1 | 2 | 3 |
| 2024 | 1 | 3 | 4 |
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Below are the most recent publications written about "Drug Discovery" by people in Profiles.
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Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology. Proc Natl Acad Sci U S A. 2024 Nov 19; 121(47):e2413108121.
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Impact of Artificial Intelligence on Clinical Research. Gastrointest Endosc Clin N Am. 2025 Apr; 35(2):445-455.
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Challenges and opportunities for early phase clinical trials of novel drug-radiotherapy combinations: recommendations from NRG Oncology, the American Society for Radiation Oncology (ASTRO), the American College of Radiology (ACR), the Sarah Cannon Research Institute, and the American College of Radiation Oncology (ACRO). Lancet Oncol. 2024 Oct; 25(10):e489-e500.
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The preclinical discovery and development of zolbetuximab for the treatment of gastric cancer. Expert Opin Drug Discov. 2024 Aug; 19(8):873-886.
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On-demand modular assembly for expedited PROTAC development. Expert Opin Drug Discov. 2024 Jul; 19(7):769-772.
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A Gram-negative-selective antibiotic that spares the gut microbiome. Nature. 2024 Jun; 630(8016):429-436.
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Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nat Chem Biol. 2024 Sep; 20(9):1199-1209.
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Targeting SARS-CoV-2 nonstructural protein 3: Function, structure, inhibition, and perspective in drug discovery. Drug Discov Today. 2024 Jan; 29(1):103832.
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ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries. J Am Chem Soc. 2023 11 22; 145(46):25283-25292.
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Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. J Infect Dis. 2023 10 03; 228(Suppl 5):S337-S354.