"Drug Discovery" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of finding chemicals for potential therapeutic use.
| Descriptor ID |
D055808
|
| MeSH Number(s) |
E05.295 H01.158.703.007.675 H01.181.466.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Discovery".
Below are MeSH descriptors whose meaning is more specific than "Drug Discovery".
This graph shows the total number of publications written about "Drug Discovery" by people in this website by year, and whether "Drug Discovery" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 1 | 2 |
| 2009 | 4 | 5 | 9 |
| 2010 | 7 | 9 | 16 |
| 2011 | 6 | 8 | 14 |
| 2012 | 8 | 5 | 13 |
| 2013 | 12 | 9 | 21 |
| 2014 | 7 | 6 | 13 |
| 2015 | 9 | 9 | 18 |
| 2016 | 7 | 10 | 17 |
| 2017 | 8 | 10 | 18 |
| 2018 | 4 | 13 | 17 |
| 2019 | 5 | 11 | 16 |
| 2020 | 5 | 8 | 13 |
| 2021 | 3 | 6 | 9 |
| 2022 | 3 | 4 | 7 |
| 2023 | 1 | 2 | 3 |
| 2024 | 1 | 2 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Drug Discovery" by people in Profiles.
-
The preclinical discovery and development of zolbetuximab for the treatment of gastric cancer. Expert Opin Drug Discov. 2024 Aug; 19(8):873-886.
-
On-demand modular assembly for expedited PROTAC development. Expert Opin Drug Discov. 2024 Jul; 19(7):769-772.
-
A Gram-negative-selective antibiotic that spares the gut microbiome. Nature. 2024 Jun; 630(8016):429-436.
-
Chemical screening by time-resolved X-ray scattering to discover allosteric probes. Nat Chem Biol. 2024 Sep; 20(9):1199-1209.
-
Targeting SARS-CoV-2 nonstructural protein 3: Function, structure, inhibition, and perspective in drug discovery. Drug Discov Today. 2024 Jan; 29(1):103832.
-
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries. J Am Chem Soc. 2023 11 22; 145(46):25283-25292.
-
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. J Infect Dis. 2023 10 03; 228(Suppl 5):S337-S354.
-
The rise of degrader drugs. Cell Chem Biol. 2023 08 17; 30(8):864-878.
-
Applications of covalent chemistry in targeted protein degradation. Chem Soc Rev. 2022 Nov 14; 51(22):9243-9261.
-
Profiling disease-selective drug targets: From proteomics to ligandomics. Drug Discov Today. 2023 03; 28(3):103430.