"Cyclodextrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homologous group of cyclic GLUCANS consisting of alpha-1,4 bound glucose units obtained by the action of cyclodextrin glucanotransferase on starch or similar substrates. The enzyme is produced by certain species of Bacillus. Cyclodextrins form inclusion complexes with a wide variety of substances.
| Descriptor ID |
D003505
|
| MeSH Number(s) |
D04.345.103 D09.301.915.400.375 D09.698.365.855.400.375
|
| Concept/Terms |
Cyclodextrins- Cyclodextrins
- Cyclomaltooligosaccharides
- Cyclodextrin Derivatives
- Derivatives, Cyclodextrin
- Cycloamylose
|
Below are MeSH descriptors whose meaning is more general than "Cyclodextrins".
Below are MeSH descriptors whose meaning is more specific than "Cyclodextrins".
This graph shows the total number of publications written about "Cyclodextrins" by people in this website by year, and whether "Cyclodextrins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclodextrins" by people in Profiles.
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Formulation and evaluation of cyclodextrin complexes for improved anticancer activity of repurposed drug: Niclosamide. Carbohydr Polym. 2019 May 15; 212:252-259.
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Synergistic interaction of paclitaxel and curcumin with cyclodextrin polymer complexation in human cancer cells. Mol Pharm. 2013 Jul 01; 10(7):2676-83.
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Contribution of AmyA, an extracellular alpha-glucan degrading enzyme, to group A streptococcal host-pathogen interaction. Mol Microbiol. 2009 Oct; 74(1):159-174.
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Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1. Cancer Biol Ther. 2005 Jan; 4(1):95-102.
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Enhancement of solubility and bioavailability of beta-lapachone using cyclodextrin inclusion complexes. Pharm Res. 2003 Oct; 20(10):1626-33.
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Femtomole immunodetection of synthetic and endogenous amyloid-beta oligomers and its application to Alzheimer's disease drug candidate screening. J Mol Neurosci. 2003; 20(3):305-13.
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Asymmetric requirement for cholesterol in receptor-bearing but not envelope-bearing membranes for fusion mediated by ecotropic murine leukemia virus. J Virol. 2002 Jul; 76(13):6701-9.
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Phase I bioequivalency study of MitoExtra and mitomycin C in patients with solid tumors. Cancer. 2001 Feb 15; 91(4):815-21.
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Cholesterol efflux-mediated signal transduction in mammalian sperm. beta-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem. 1999 Jan 29; 274(5):3235-42.
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A thermodynamic study of the binding of linear and cyclic oligosaccharides to the maltodextrin-binding protein of Escherichia coli. Biophys Chem. 1998 Feb 16; 70(2):101-8.