Cholestanetriol 26-Monooxygenase
"Cholestanetriol 26-Monooxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NAPH-dependent cytochrome P450 enzyme that catalyzes the oxidation of the side chain of sterol intermediates such as the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol.
| Descriptor ID |
D053493
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| MeSH Number(s) |
D08.244.453.499.750 D08.244.453.915.149 D08.811.682.690.708.170.493.750 D08.811.682.690.708.170.915.150 D12.776.422.220.453.499.750 D12.776.422.220.453.915.150
|
| Concept/Terms |
Cholestanetriol 26-Monooxygenase- Cholestanetriol 26-Monooxygenase
- Cholestanetriol 26 Monooxygenase
- C27-Steroid 26-Hydroxylase
- C27 Steroid 26 Hydroxylase
- Cytochrome P-450 Sterol 26-Hydroxylase
- Cytochrome P 450 Sterol 26 Hydroxylase
- 5-beta-Cholestane-3-alpha,7-alpha,12-alpha-triol 27-Hydroxylase
- Steroid 27-Hydroxylase
- Steroid 27 Hydroxylase
- Sterol 27-Hydroxylase
- Sterol 27 Hydroxylase
- Vitamin D3 25-Hydroxylase
- Vitamin D3 25 Hydroxylase
- Sterol 26-Hydroxylase
- Sterol 26 Hydroxylase
- Steroid 25-Hydroxylase
- Steroid 25 Hydroxylase
- Cytochrome P-450 Steroid 27-Hydroxylase
- Cytochrome P 450 Steroid 27 Hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Cholestanetriol 26-Monooxygenase".
Below are MeSH descriptors whose meaning is more specific than "Cholestanetriol 26-Monooxygenase".
This graph shows the total number of publications written about "Cholestanetriol 26-Monooxygenase" by people in this website by year, and whether "Cholestanetriol 26-Monooxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholestanetriol 26-Monooxygenase" by people in Profiles.
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CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer. Cancer Res. 2017 04 01; 77(7):1662-1673.
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Lifestyle and Other Factors Explain One-Half of the Variability in the Serum 25-Hydroxyvitamin D Response to Cholecalciferol Supplementation in Healthy Adults. J Nutr. 2016 Nov; 146(11):2312-2324.
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Apparent underdiagnosis of Cerebrotendinous Xanthomatosis revealed by analysis of ~60,000 human exomes. Mol Genet Metab. 2015 Dec; 116(4):298-304.
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Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial. J Clin Endocrinol Metab. 2014 Oct; 99(10):E2133-7.
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Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TR?1-governed pathway. J Clin Invest. 2014 May; 124(5):1976-86.
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27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science. 2013 Nov 29; 342(6162):1094-8.
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Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G652-60.
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The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology. 2010 Aug; 151(8):3675-85.
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Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters. Atherosclerosis. 2010 Mar; 209(1):111-7.
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Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G1009-16.