"Steroid 21-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013255
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| MeSH Number(s) |
D08.244.453.493.500 D08.244.453.915.760 D08.811.682.690.708.170.463.500 D08.811.682.690.708.170.915.760 D12.776.422.220.453.493.500 D12.776.422.220.453.915.760
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| Concept/Terms |
Steroid 21-Hydroxylase- Steroid 21-Hydroxylase
- Cytochrome P-450 21-Hydroxylase
- Cytochrome P 450 21 Hydroxylase
- Cytochrome P-450(c-21)
- Progesterone 21-Hydroxylase
- Progesterone 21 Hydroxylase
- Cytochrome P-450 CYP21
- Cytochrome P 450 CYP21
- Steroid 21-Monooxygenase
- Steroid 21 Monooxygenase
- Cytochrome P450c21
- Cytochrome P-450 c21
- Cytochrome P 450 c21
- P-450 c21, Cytochrome
- 21-Hydroxylase
- 21 Hydroxylase
- Steroid-21-Hydroxylase
- Steroid 21 Hydroxylase
|
Below are MeSH descriptors whose meaning is more general than "Steroid 21-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 21-Hydroxylase".
This graph shows the total number of publications written about "Steroid 21-Hydroxylase" by people in this website by year, and whether "Steroid 21-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Steroid 21-Hydroxylase" by people in Profiles.
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Adrenal cortical hyperplasia: diagnostic workup, subtypes, imaging features and mimics. Br J Radiol. 2017 Nov; 90(1079):20170330.
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A case study in unethical transgressive bioethics: "Letter of concern from bioethicists" about the prenatal administration of dexamethasone. Am J Bioeth. 2010 Sep; 10(9):35-45.
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Expression of paralogs of cytochrome P 450 21a1 pseudogene (Cyp21a1-ps) and endogenous retrovirus SC1 (SC1) in the rat ovary during the ovulatory process. J Endocrinol. 2008 Jul; 198(1):231-41.
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E380D: a novel point mutation of CYP21 in an HLA-homozygous patient with salt-losing congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Hum Mutat. 1997; 9(2):181-2.
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Molecular heterogeneity of complement component C4-null and 21-hydroxylase genes in systemic lupus erythematosus. Arthritis Rheum. 1988 Jun; 31(6):736-44.