TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology

    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging

    Collapse Overview 
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    We are interested in epigenomic regulation of metabolism and cognitive functions by physical exercise, diet, and the circadian clock
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ye H, Feng B, Wang C, Saito K, Yang Y, Ibrahimi L, Schaul S, Patel N, Saenz L, Luo P, Lai P, Torres V, Kota M, Dixit D, Cai X, Qu N, Hyseni I, Yu K, Jiang Y, Tong Q, Sun Z, Arenkiel BR, He Y, Xu P, Xu Y. An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity. Sci Adv. 2022 Jan 21; 8(3):eabk0185. PMID: 35044814; PMCID: PMC8769556.
      Citations: 2     Fields:    
    2. Song S, Tien CL, Cui H, Basil P, Zhu N, Gong Y, Li W, Li H, Fan Q, Min Choi J, Luo W, Xue Y, Cao R, Zhou W, Ortiz AR, Stork B, Mundra V, Putluri N, York B, Chu M, Chang J, Yun Jung S, Xie L, Song J, Zhang L, Sun Z. Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox. Circulation. 2022 02 08; 145(6):448-464. PMID: 35034472; PMCID: PMC8812427.
      Citations: 1     Fields:    Translation:HumansAnimals
    3. Yang Y, He Y, Liu H, Zhou W, Wang C, Xu P, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Fukuda M, Tong Q, Xu J, Sun Z, O'Malley BW, Xu Y. Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Rep. 2021 12 07; 37(10):110075. PMID: 34879284; PMCID: PMC8715676.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Mao H, Li L, Fan Q, Angelini A, Saha PK, Coarfa C, Rajapakshe K, Perera D, Cheng J, Wu H, Ballantyne CM, Sun Z, Xie L, Pi X. Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nat Commun. 2021 09 06; 12(1):5296. PMID: 34489478; PMCID: PMC8421392.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. He Y, Cai X, Liu H, Conde KM, Xu P, Li Y, Wang C, Yu M, He Y, Liu H, Liang C, Yang T, Yang Y, Yu K, Wang J, Zheng R, Liu F, Sun Z, Heisler L, Wu Q, Tong Q, Zhu C, Shu G, Xu Y. 5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding. Mol Psychiatry. 2021 12; 26(12):7211-7224. PMID: 34290371; PMCID: PMC8776930.
      Citations: 3     Fields:    Translation:Cells
    6. He Y, Liu H, Yin N, Yang Y, Wang C, Yu M, Liu H, Liang C, Wang J, Tu L, Zhang N, Wang L, He Y, Fukuda M, Wu Q, Sun Z, Tong Q, Xu Y. Barbadin Potentiates Long-Term Effects of Lorcaserin on POMC Neurons and Weight Loss. J Neurosci. 2021 06 30; 41(26):5734-5746. PMID: 34031163; PMCID: PMC8244968.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Yin H, Kang Z, Zhang Y, Gong Y, Liu M, Xue Y, He W, Wang Y, Zhang S, Xu Q, Fu K, Zheng B, Xie J, Zhang J, Wang Y, Lin M, Zhang Y, Feng H, Xin C, Guan Y, Huang C, Guo X, Wang PJ, Baur JA, Zheng K, Sun Z, Ye L. HDAC3 controls male fertility through enzyme-independent transcriptional regulation at the meiotic exit of spermatogenesis. Nucleic Acids Res. 2021 05 21; 49(9):5106-5123. PMID: 33939832; PMCID: PMC8136829.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Zhang Z, Liu S, Qi Y, Aluo Z, Zhang L, Yu L, Li Q, Luo Z, Sun Z, Zhou L, Li Y. Calcium supplementation relieves high-fat diet-induced liver steatosis by reducing energy metabolism and promoting lipolysis. J Nutr Biochem. 2021 08; 94:108645. PMID: 33838230.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    9. Ding G, Li X, Hou X, Zhou W, Gong Y, Liu F, He Y, Song J, Wang J, Basil P, Li W, Qian S, Saha P, Wang J, Cui C, Yang T, Zou K, Han Y, Amos CI, Xu Y, Chen L, Sun Z. REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 2021 04; 592(7856):763-767. PMID: 33762728; PMCID: PMC8085086.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    10. Cox AR, Chernis N, Kim KH, Masschelin PM, Saha PK, Briley SM, Sharp R, Li X, Felix JB, Sun Z, Moore DD, Pangas SA, Hartig SM. Ube2i deletion in adipocytes causes lipoatrophy in mice. Mol Metab. 2021 06; 48:101221. PMID: 33771728; PMCID: PMC8080079.
      Citations: 2     Fields:    Translation:AnimalsCells
    11. Gong Y, Xue Y, Li X, Zhang Z, Zhou W, Marcolongo P, Benedetti A, Mao S, Han L, Ding G, Sun Z. Inter- and Transgenerational Effects of Paternal Exposure to Inorganic Arsenic. Adv Sci (Weinh). 2021 04; 8(7):2002715. PMID: 33854880; PMCID: PMC8025034.
      Citations: 4     Fields:    Translation:AnimalsPHPublic Health
    12. Wang C, Zhou W, He Y, Yang T, Xu P, Yang Y, Cai X, Wang J, Liu H, Yu M, Liang C, Yang T, Liu H, Fukuda M, Tong Q, Wu Q, Sun Z, He Y, Xu Y. AgRP neurons trigger long-term potentiation and facilitate food seeking. Transl Psychiatry. 2021 01 05; 11(1):11. PMID: 33414382; PMCID: PMC7791100.
      Citations: 5     Fields:    Translation:AnimalsCells
    13. Sun Z, Xu Y. Nuclear Receptor Coactivators (NCOAs) and Corepressors (NCORs) in the Brain. Endocrinology. 2020 08 01; 161(8). PMID: 32449767; PMCID: PMC7351129.
      Citations: 9     Fields:    Translation:HumansAnimals
    14. He Y, Xu P, Wang C, Xia Y, Yu M, Yang Y, Yu K, Cai X, Qu N, Saito K, Wang J, Hyseni I, Robertson M, Piyarathna B, Gao M, Khan SA, Liu F, Chen R, Coarfa C, Zhao Z, Tong Q, Sun Z, Xu Y. Estrogen receptor-a expressing neurons in the ventrolateral VMH regulate glucose balance. Nat Commun. 2020 05 01; 11(1):2165. PMID: 32358493; PMCID: PMC7195451.
      Citations: 18     Fields:    Translation:AnimalsCells
    15. Kong Y, Zhou W, Sun Z. Nuclear receptor corepressors in intellectual disability and autism. Mol Psychiatry. 2020 10; 25(10):2220-2236. PMID: 32034290; PMCID: PMC7842082.
      Citations: 6     Fields:    Translation:HumansAnimals
    16. Liu J, Ding G, Zou K, Jiang Z, Zhang J, Lu Y, Pignata A, Venner E, Liu P, Liu Z, Wangler MF, Sun Z. Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia. Mol Genet Genomic Med. 2020 03; 8(3):e1130. PMID: 31971667; PMCID: PMC7057095.
      Citations: 3     Fields:    Translation:Humans
    17. Li X, Yang T, Sun Z. Hormesis in Health and Chronic Diseases. Trends Endocrinol Metab. 2019 12; 30(12):944-958. PMID: 31521464; PMCID: PMC6875627.
      Citations: 6     Fields:    Translation:HumansAnimals
    18. Qu N, He Y, Wang C, Xu P, Yang Y, Cai X, Liu H, Yu K, Pei Z, Hyseni I, Sun Z, Fukuda M, Li Y, Tian Q, Xu Y. A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia. Mol Psychiatry. 2020 05; 25(5):1006-1021. PMID: 31485012; PMCID: PMC7056580.
      Citations: 23     Fields:    Translation:Animals
    19. Luo Z, Zhang Z, Tai L, Zhang L, Zhou L, Sun Z. Comprehensive analysis of differences of N6-methyladenosine RNA methylomes between high-fat-fed and normal mouse livers. Epigenomics. 2019 08; 11(11):1267-1282. PMID: 31290331.
      Citations: 26     Fields:    Translation:AnimalsCells
    20. Colleluori G, Aguirre L, Phadnis U, Fowler K, Armamento-Villareal R, Sun Z, Brunetti L, Hyoung Park J, Kaipparettu BA, Putluri N, Auetumrongsawat V, Yarasheski K, Qualls C, Villareal DT. Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss. Cell Metab. 2019 08 06; 30(2):261-273.e6. PMID: 31279675; PMCID: PMC6685749.
      Citations: 21     Fields:    Translation:Humans
    21. Gong Y, Liu J, Xue Y, Zhuang Z, Qian S, Zhou W, Li X, Qian J, Ding G, Sun Z. Non-monotonic dose-response effects of arsenic on glucose metabolism. Toxicol Appl Pharmacol. 2019 08 15; 377:114605. PMID: 31170414; PMCID: PMC6731945.
      Citations: 5     Fields:    Translation:Animals
    22. Li W, Sun Z. Mechanism of Action for HDAC Inhibitors-Insights from Omics Approaches. Int J Mol Sci. 2019 Apr 01; 20(7). PMID: 30939743; PMCID: PMC6480157.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    23. Zheng Y, Qu H, Xiong X, Wang Y, Liu X, Zhang L, Liao X, Liao Q, Sun Z, Ouyang Q, Yang G, Zhu Z, Xu J, Zheng H. Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Contributes to Hepatic Steatosis. Hepatology. 2019 07; 70(1):84-97. PMID: 30653687; PMCID: PMC6597300.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    24. Song S, Wen Y, Tong H, Loro E, Gong Y, Liu J, Hong S, Li L, Khurana TS, Chu M, Sun Z. The HDAC3 enzymatic activity regulates skeletal muscle fuel metabolism. J Mol Cell Biol. 2019 02 01; 11(2):133-143. PMID: 30428023; PMCID: PMC6392100.
      Citations: 14     Fields:    Translation:Animals
    25. Zhou W, He Y, Rehman AU, Kong Y, Hong S, Ding G, Yalamanchili HK, Wan YW, Paul B, Wang C, Gong Y, Zhou W, Liu H, Dean J, Scalais E, O'Driscoll M, Morton JEV, DDD study, Hou X, Wu Q, Tong Q, Liu Z, Liu P, Xu Y, Sun Z. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019 02; 22(2):205-217. PMID: 30664766; PMCID: PMC6361549.
      Citations: 24     Fields:    Translation:AnimalsCells
    26. Zhu Z, Yue Q, Xie J, Zhang S, He W, Bai S, Tian S, Zhang Y, Xiong M, Sun Z, Huang C, Li Y, Zheng K, Ye L. Rapamycin-mediated mTOR inhibition impairs silencing of sex chromosomes and the pachytene piRNA pathway in the mouse testis. Aging (Albany NY). 2019 01 13; 11(1):185-208. PMID: 30636722; PMCID: PMC6339782.
      Citations: 4     Fields:    Translation:AnimalsCells
    27. Bai S, Fu K, Yin H, Cui Y, Yue Q, Li W, Cheng L, Tan H, Liu X, Guo Y, Zhang Y, Xie J, He W, Wang Y, Feng H, Xin C, Zhang J, Lin M, Shen B, Sun Z, Guo X, Zheng K, Ye L. Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. Development. 2018 07 04; 145(13). PMID: 29866902; PMCID: PMC6053656.
      Citations: 15     Fields:    Translation:AnimalsCells
    28. Cui C, Jiang X, Ju W, Wang J, Wang D, Sun Z, Chen M. Atrial remodeling and metabolic dysfunction in idiopathic isolated fibrotic atrial cardiomyopathy. Int J Cardiol. 2018 Aug 15; 265:155-161. PMID: 29706431; PMCID: PMC6188944.
      Citations:    Fields:    Translation:Humans
    29. Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299. PMID: 29480818; PMCID: PMC5873887.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    30. Ding G, Gong Y, Eckel-Mahan KL, Sun Z. Central Circadian Clock Regulates Energy Metabolism. Adv Exp Med Biol. 2018; 1090:79-103. PMID: 30390286; PMCID: PMC6324174.
      Citations: 5     Fields:    Translation:Animals
    31. Zhang Y, Papazyan R, Damle M, Fang B, Jager J, Feng D, Peed LC, Guan D, Sun Z, Lazar MA. The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORa/?. Genes Dev. 2017 06 15; 31(12):1202-1211. PMID: 28747429; PMCID: PMC5558923.
      Citations: 23     Fields:    Translation:AnimalsCells
    32. Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang CC, Qian J, Lie N, Lanzillotta C, Rabinowitz JD, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018 08 15; 471:22-32. PMID: 28554803; PMCID: PMC5702591.
      Citations: 3     Fields:    Translation:AnimalsCells
    33. Xiong M, Zhu Z, Tian S, Zhu R, Bai S, Fu K, Davis JG, Sun Z, Baur JA, Zheng K, Ye L. Conditional ablation of Raptor in the male germline causes infertility due to meiotic arrest and impaired inactivation of sex chromosomes. FASEB J. 2017 09; 31(9):3934-3949. PMID: 28490482.
      Citations: 4     Fields:    Translation:AnimalsCells
    34. Cao R, Sun Z. Intergenerational Effects of Endocrine Disorder on Metabolism. EBioMedicine. 2017 02; 16:18-19. PMID: 28163044; PMCID: PMC5474511.
      Citations:    Fields:    
    35. Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med. 2017 Feb; 23(2):223-234. PMID: 27991918; PMCID: PMC5540654.
      Citations: 43     Fields:    Translation:AnimalsCells
    36. Papazyan R, Sun Z, Kim YH, Titchenell PM, Hill DA, Lu W, Damle M, Wan M, Zhang Y, Briggs ER, Rabinowitz JD, Lazar MA. Physiological Suppression of Lipotoxic Liver Damage?by Complementary Actions of HDAC3 and?SCAP/SREBP. Cell Metab. 2016 12 13; 24(6):863-874. PMID: 27866836; PMCID: PMC5159233.
      Citations: 32     Fields:    Translation:AnimalsCells
    37. Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, He D, Zheng T, Zhou X, Hassan A, Ma Z, Xin M, Sun Z, Lazar MA, Goldman SA, Olson EN, Richard Lu Q. Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch. Dev Cell. 2016 Jun 20; 37(6):582. PMID: 27326936.
      Citations: 3     Fields:    
    38. Wang C, Wang L, Liu J, Song J, Sun Y, Lin P, Liang K, Liu F, He T, Sun Z, Hou X, Chen L. Irisin modulates the association of interleukin-17A with the presence of non-proliferative diabetic retinopathy in patients with type 2 diabetes. Endocrine. 2016 Aug; 53(2):459-64. PMID: 26940815.
      Citations: 9     Fields:    Translation:Humans
    39. Zhang Y, Fang B, Emmett MJ, Damle M, Sun Z, Feng D, Armour SM, Remsberg JR, Jager J, Soccio RE, Steger DJ, Lazar MA. GENE REGULATION. Discrete functions of nuclear receptor Rev-erba couple metabolism to the clock. Science. 2015 Jun 26; 348(6242):1488-92. PMID: 26044300; PMCID: PMC4613749.
      Citations: 149     Fields:    Translation:AnimalsCells
    40. Zhu L, Zou F, Yang Y, Xu P, Saito K, Othrell Hinton A, Yan X, Ding H, Wu Q, Fukuda M, Sun Z, Tong Q, Xu Y. Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology. 2015 Jun; 156(6):2114-23. PMID: 25807042; PMCID: PMC4430614.
      Citations: 18     Fields:    Translation:Animals
    41. Fang B, Everett LJ, Jager J, Briggs E, Armour SM, Feng D, Roy A, Gerhart-Hines Z, Sun Z, Lazar MA. Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo. Cell. 2014 Nov 20; 159(5):1140-1152. PMID: 25416951; PMCID: PMC4243056.
      Citations: 116     Fields:    Translation:AnimalsCells
    42. Lewandowski SL, Janardhan HP, Smee KM, Bachman M, Sun Z, Lazar MA, Trivedi CM. Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis. Hum Mol Genet. 2014 Jul 15; 23(14):3801-9. PMID: 24565863; PMCID: PMC4065153.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    43. Sun Z, Feng D, Fang B, Mullican SE, You SH, Lim HW, Everett LJ, Nabel CS, Li Y, Selvakumaran V, Won KJ, Lazar MA. Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor. Mol Cell. 2013 Dec 26; 52(6):769-82. PMID: 24268577; PMCID: PMC3877208.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    44. Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Mol Cell. 2013 Jul 11; 51(1):68-79. PMID: 23727018; PMCID: PMC3732832.
      Citations: 38     Fields:    Translation:HumansCells
    45. You SH, Lim HW, Sun Z, Broache M, Won KJ, Lazar MA. Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3?in vivo. Nat Struct Mol Biol. 2013 Feb; 20(2):182-7. PMID: 23292142; PMCID: PMC3565028.
      Citations: 96     Fields:    Translation:AnimalsCells
    46. Sun Z, Lazar MA. Dissociating fatty liver and diabetes. Trends Endocrinol Metab. 2013 Jan; 24(1):4-12. PMID: 23043895; PMCID: PMC3532558.
      Citations: 67     Fields:    Translation:HumansAnimals
    47. Sun Z, Miller RA, Patel RT, Chen J, Dhir R, Wang H, Zhang D, Graham MJ, Unterman TG, Shulman GI, Sztalryd C, Bennett MJ, Ahima RS, Birnbaum MJ, Lazar MA. Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nat Med. 2012 Jun; 18(6):934-42. PMID: 22561686; PMCID: PMC3411870.
      Citations: 162     Fields:    Translation:AnimalsCells
    48. Sun Z, Singh N, Mullican SE, Everett LJ, Li L, Yuan L, Liu X, Epstein JA, Lazar MA. Diet-induced lethality due to deletion of the Hdac3 gene in heart and skeletal muscle. J Biol Chem. 2011 Sep 23; 286(38):33301-9. PMID: 21808063; PMCID: PMC3190900.
      Citations: 53     Fields:    Translation:HumansAnimals
    49. Feng D, Liu T, Sun Z, Bugge A, Mullican SE, Alenghat T, Liu XS, Lazar MA. A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science. 2011 Mar 11; 331(6022):1315-9. PMID: 21393543; PMCID: PMC3389392.
      Citations: 340     Fields:    Translation:AnimalsCells
    50. Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Mol Cell Biol. 2011 May; 31(9):1800-11. PMID: 21383067; PMCID: PMC3133232.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    51. Hur W, Sun Z, Jiang T, Mason DE, Peters EC, Zhang DD, Luesch H, Schultz PG, Gray NS. A small-molecule inducer of the antioxidant response element. Chem Biol. 2010 May 28; 17(5):537-47. PMID: 20534351.
      Citations: 36     Fields:    Translation:HumansCells
    52. Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol. 2010 Jul; 30(13):3275-85. PMID: 20421418; PMCID: PMC2897585.
      Citations: 360     Fields:    Translation:HumansAnimalsCells
    53. Villeneuve NF, Sun Z, Chen W, Zhang DD. Nrf2 and p21 regulate the fine balance between life and death by controlling ROS levels. Cell Cycle. 2009 Oct 15; 8(20):3255-6. PMID: 19806015; PMCID: PMC3918967.
      Citations: 41     Fields:    Translation:Cells
    54. Sun Z, Huang Z, Zhang DD. Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. PLoS One. 2009 Aug 11; 4(8):e6588. PMID: 19668370; PMCID: PMC2719090.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    55. Chen W, Sun Z, Wang XJ, Jiang T, Huang Z, Fang D, Zhang DD. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. Mol Cell. 2009 Jun 26; 34(6):663-73. PMID: 19560419; PMCID: PMC2714804.
      Citations: 272     Fields:    Translation:AnimalsCells
    56. Sun Z, Chin YE, Zhang DD. Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol Cell Biol. 2009 May; 29(10):2658-72. PMID: 19273602; PMCID: PMC2682049.
      Citations: 165     Fields:    Translation:HumansAnimalsCells
    57. Lau A, Villeneuve NF, Sun Z, Wong PK, Zhang DD. Dual roles of Nrf2 in cancer. Pharmacol Res. 2008 Nov-Dec; 58(5-6):262-70. PMID: 18838122; PMCID: PMC2652397.
      Citations: 282     Fields:    Translation:HumansAnimals
    58. Du Y, Villeneuve NF, Wang XJ, Sun Z, Chen W, Li J, Lou H, Wong PK, Zhang DD. Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. Environ Health Perspect. 2008 Sep; 116(9):1154-61. PMID: 18795156; PMCID: PMC2535615.
      Citations: 43     Fields:    Translation:HumansCells
    59. Wondrak GT, Cabello CM, Villeneuve NF, Zhang S, Ley S, Li Y, Sun Z, Zhang DD. Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress. Free Radic Biol Med. 2008 Aug 15; 45(4):385-95. PMID: 18482591; PMCID: PMC3710742.
      Citations: 40     Fields:    Translation:HumansCells
    60. Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK, Zhang DD. Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis. 2008 Jun; 29(6):1235-43. PMID: 18413364; PMCID: PMC3312612.
      Citations: 359     Fields:    Translation:HumansCells
    61. Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD. Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicol Appl Pharmacol. 2008 Aug 01; 230(3):383-9. PMID: 18417180; PMCID: PMC2610481.
      Citations: 56     Fields:    Translation:HumansCells
    62. Wang XJ, Sun Z, Chen W, Eblin KE, Gandolfi JA, Zhang DD. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicol Appl Pharmacol. 2007 Dec 01; 225(2):206-13. PMID: 17765279; PMCID: PMC2610476.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    63. Sun Z, Zhang S, Chan JY, Zhang DD. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Mol Cell Biol. 2007 Sep; 27(18):6334-49. PMID: 17636022; PMCID: PMC2099624.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    64. Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. J Biol Chem. 2005 Aug 26; 280(34):30091-9. PMID: 15983046.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
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