Acid Sensing Ion Channels
"Acid Sensing Ion Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.
| Descriptor ID |
D062565
|
| MeSH Number(s) |
D12.776.157.530.400.875.050 D12.776.543.550.450.875.050 D12.776.543.585.400.875.050 D12.776.631.024
|
| Concept/Terms |
Acid Sensing Ion Channels- Acid Sensing Ion Channels
- ASIC Channel
- Proton-Gated Sodium Channels
- Proton Gated Sodium Channels
- Sodium Channels, Proton-Gated
- Acid-Sensing Ion Channels
|
Below are MeSH descriptors whose meaning is more general than "Acid Sensing Ion Channels".
Below are MeSH descriptors whose meaning is more specific than "Acid Sensing Ion Channels".
This graph shows the total number of publications written about "Acid Sensing Ion Channels" by people in this website by year, and whether "Acid Sensing Ion Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acid Sensing Ion Channels" by people in Profiles.
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Follistatin mediates learning and synaptic plasticity via regulation of Asic4 expression in the hippocampus. Proc Natl Acad Sci U S A. 2021 09 28; 118(39).
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Assessment of Pediatric Optic Neuritis Visual Acuity Outcomes at 6 Months. JAMA Ophthalmol. 2020 12 01; 138(12):1253-1261.
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Ion Permeation and Mechanotransduction Mechanisms of Mechanosensitive Piezo Channels. Neuron. 2016 Mar 16; 89(6):1248-1263.
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Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum. Neurobiol Dis. 2011 Aug; 43(2):446-54.
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Identification of protein domains that control proton and calcium sensitivity of ASIC1a. J Biol Chem. 2009 Oct 09; 284(41):27899-27907.
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17p11.2p12 triplication and del(17)q11.2q12 in a severely affected child with dup(17)p11.2p12 syndrome. Clin Genet. 2007 Jul; 72(1):47-58.
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A module of negative feedback regulators defines growth factor signaling. Nat Genet. 2007 Apr; 39(4):503-12.