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Neil J. McKenna

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
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    U24DK097748     (O'MALLEY, BERT W)Sep 17, 2012 - Aug 31, 2018
    NIH/NIDDK
    A Hub for the Nuclear Receptor Signaling Atlas1
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ochsner SA, Abraham D, Martin K, Ding W, McOwiti A, Kankanamge W, Wang Z, Andreano K, Hamilton RA, Chen Y, Hamilton A, Gantner ML, Dehart M, Qu S, Hilsenbeck SG, Becnel LB, Bridges D, Ma'ayan A, Huss JM, Stossi F, Foulds CE, Kralli A, McDonnell DP, McKenna NJ. The Signaling Pathways Project, an integrated 'omics knowledgebase for mammalian cellular signaling pathways. Sci Data. 2019 10 31; 6(1):252. PMID: 31672983.
      View in: PubMed
    2. Jagodnik KM, Koplev S, Jenkins SL, Ohno-Machado L, Paten B, Schurer SC, Dumontier M, Verborgh R, Bui A, Ping P, McKenna NJ, Madduri R, Pillai A, Ma'ayan A. Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop. J Biomed Inform. 2017 07; 71:49-57. PMID: 28501646.
      View in: PubMed
    3. Becnel LB, Ochsner SA, Darlington YF, McOwiti A, Kankanamge WH, Dehart M, Naumov A, McKenna NJ. Discovering relationships between nuclear receptor signaling pathways, genes, and tissues in Transcriptomine. Sci Signal. 2017 Apr 25; 10(476). PMID: 28442630.
      View in: PubMed
    4. Darlington YF, Naumov A, McOwiti A, Kankanamge WH, Becnel LB, McKenna NJ. Improving the discoverability, accessibility, and citability of omics datasets: a case report. J Am Med Inform Assoc. 2017 03 01; 24(2):388-393. PMID: 27413121.
      View in: PubMed
    5. Ochsner SA, Tsimelzon A, Dong J, Coarfa C, McKenna NJ. Research Resource: A Reference Transcriptome for Constitutive Androstane Receptor and Pregnane X Receptor Xenobiotic Signaling. Mol Endocrinol. 2016 Aug; 30(8):937-48. PMID: 27409825.
      View in: PubMed
    6. McKenna NJ. Research Resources for Nuclear Receptor Signaling Pathways. Mol Pharmacol. 2016 Aug; 90(2):153-9. PMID: 27216565.
      View in: PubMed
    7. Becnel LB, Darlington YF, Ochsner SA, Easton-Marks JR, Watkins CM, McOwiti A, Kankanamge WH, Wise MW, DeHart M, Margolis RN, McKenna NJ. Nuclear Receptor Signaling Atlas: Opening Access to the Biology of Nuclear Receptor Signaling Pathways. PLoS One. 2015; 10(9):e0135615. PMID: 26325041.
      View in: PubMed
    8. McKenna NJ, Evans RM, O'Malley BW. Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research. Nucl Recept Signal. 2014; 12:e006. PMID: 25614732.
      View in: PubMed
    9. Hartig SM, Feng Q, Ochsner SA, Xiao R, McKenna NJ, McGuire SE, He B. Androgen receptor agonism promotes an osteogenic gene program in preadipocytes. Biochem Biophys Res Commun. 2013 May 03; 434(2):357-62. PMID: 23567971.
      View in: PubMed
    10. Defranco DB, Margolis R, McKenna N. Editorial: molecular endocrinology articles in the spotlight for October 2012. Mol Endocrinol. 2012 Oct; 26(10):1645. PMID: 23023930.
      View in: PubMed
    11. Hartig SM, He B, Newberg JY, Ochsner SA, Loose DS, Lanz RB, McKenna NJ, Buehrer BM, McGuire SE, Marcelli M, Mancini MA. Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes. Chem Biol. 2012 Sep 21; 19(9):1126-41. PMID: 22999881.
      View in: PubMed
    12. Pradhan A, Khalaf H, Ochsner SA, Sreenivasan R, Koskinen J, Karlsson M, Karlsson J, McKenna NJ, Orbán L, Olsson PE. Activation of NF-?B protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish. J Biol Chem. 2012 Nov 02; 287(45):37926-38. PMID: 22988238.
      View in: PubMed
    13. Becnel LB, McKenna NJ. Minireview: progress and challenges in proteomics data management, sharing, and integration. Mol Endocrinol. 2012 Oct; 26(10):1660-74. PMID: 22902541.
      View in: PubMed
    14. Ochsner SA, Watkins CM, McOwiti A, Xu X, Darlington YF, Dehart MD, Cooney AJ, Steffen DL, Becnel LB, McKenna NJ. Transcriptomine, a web resource for nuclear receptor signaling transcriptomes. Physiol Genomics. 2012 Sep 01; 44(17):853-63. PMID: 22786849.
      View in: PubMed
    15. McKenna NJ, Howard CL, Aufiero M, Easton-Marks J, Steffen DL, Becnel LB, Magnuson MA, McIndoe RA, Cartailler JP. Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia. Mol Endocrinol. 2012 Oct; 26(10):1675-81. PMID: 22734043.
      View in: PubMed
    16. McKenna NJ. EMBO Retinoids 2011: Mechanisms, biology and pathology of signaling by retinoic acid and retinoic acid receptors. Nucl Recept Signal. 2012; 10:e003. PMID: 22438793.
      View in: PubMed
    17. Anakk S, Watanabe M, Ochsner SA, McKenna NJ, Finegold MJ, Moore DD. Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis. J Clin Invest. 2011 Jan; 121(1):86-95. PMID: 21123943.
      View in: PubMed
    18. McKenna NJ. Discovery-driven research and bioinformatics in nuclear receptor and coregulator signaling. Biochim Biophys Acta. 2011 Aug; 1812(8):808-17. PMID: 21029773.
      View in: PubMed
    19. McKenna NJ, O'Malley BW. SnapShot: NR coregulators. Cell. 2010 Oct 01; 143(1):172-172.e1. PMID: 20887900.
      View in: PubMed
    20. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors II. Cell. 2010 Sep 17; 142(6):986.e1. PMID: 20850017.
      View in: PubMed
    21. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors I. Cell. 2010 Sep 03; 142(5):822-822.e1. PMID: 20813267.
      View in: PubMed
    22. Ochsner SA, Watkins CM, LaGrone BS, Steffen DL, McKenna NJ. Research resource: Tissue-specific transcriptomics and cistromics of nuclear receptor signaling: a web research resource. Mol Endocrinol. 2010 Oct; 24(10):2065-9. PMID: 20685849.
      View in: PubMed
    23. DeFranco DB, McKenna NJ. Signals from NURSA. Mol Endocrinol. 2009 Dec; 23(12):1939. PMID: 19934347.
      View in: PubMed
    24. McKenna NJ, DeFranco DB. Molecular endocrinology: A portal for enhanced access and utility of the nuclear receptor signaling atlas (NURSA) web resource. Mol Endocrinol. 2009 Jun; 23(6):739. PMID: 19470797.
      View in: PubMed
    25. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650.
      View in: PubMed
    26. Schupp M, Cristancho AG, Lefterova MI, Hanniman EA, Briggs ER, Steger DJ, Qatanani M, Curtin JC, Schug J, Ochsner SA, McKenna NJ, Lazar MA. Re-expression of GATA2 cooperates with peroxisome proliferator-activated receptor-gamma depletion to revert the adipocyte phenotype. J Biol Chem. 2009 Apr 03; 284(14):9458-64. PMID: 19136559.
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    27. Ochsner SA, Steffen DL, Hilsenbeck SG, Chen ES, Watkins C, McKenna NJ. GEMS (Gene Expression MetaSignatures), a Web resource for querying meta-analysis of expression microarray datasets: 17beta-estradiol in MCF-7 cells. Cancer Res. 2009 Jan 01; 69(1):23-6. PMID: 19117983.
      View in: PubMed
    28. Ochsner SA, Steffen DL, Stoeckert CJ, McKenna NJ. Much room for improvement in deposition rates of expression microarray datasets. Nat Methods. 2008 Dec; 5(12):991. PMID: 19034265.
      View in: PubMed
    29. O'Malley BW, McKenna NJ. Coactivators and corepressors: what's in a name? Mol Endocrinol. 2008 Oct; 22(10):2213-4. PMID: 18701638.
      View in: PubMed
    30. Lanz RB, Jericevic Z, Zuercher WJ, Watkins C, Steffen DL, Margolis R, McKenna NJ. Nuclear Receptor Signaling Atlas (www.nursa.org): hyperlinking the nuclear receptor signaling community. Nucleic Acids Res. 2006 Jan 01; 34(Database issue):D221-6. PMID: 16381851.
      View in: PubMed
    31. McKenna NJ, O'Malley BW. Teaching resources. An interactive course in nuclear receptor signaling: concepts and models. Sci STKE. 2005 Aug 30; 2005(299):tr22. PMID: 16131668.
      View in: PubMed
    32. Cheskis BJ, McKenna NJ, Wong CW, Wong J, Komm B, Lyttle CR, O'Malley BW. Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members. J Biol Chem. 2003 Apr 11; 278(15):13271-7. PMID: 12540843.
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    33. McKenna NJ, O'Malley BW. Minireview: nuclear receptor coactivators--an update. Endocrinology. 2002 Jul; 143(7):2461-5. PMID: 12072374.
      View in: PubMed
    34. McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 2002 Feb 22; 108(4):465-74. PMID: 11909518.
      View in: PubMed
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