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George Gerald Rodney Jr.

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Physiology & Biophysics
DivisionMolecular Physiology & Biophysics
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    F32NS044636     (RODNEY, GEORGE G)Mar 21, 2003
    NIH/NINDS
    Regulation of Calcium Release by Calmodulin in Muscle
    Role: Principal Investigator

    K01AR051519     (RODNEY, GEORGE G)May 1, 2005 - Apr 30, 2011
    NIH/NIAMS
    Calmodulin &Calmodulin Binding Domains in E-C Coupling
    Role: Principal Investigator

    R01AR053349     (HAMILTON, SUSAN L)Dec 1, 2005 - Mar 31, 2021
    NIH/NIAMS
    Basis of Muscle Dysfunction in Malignant Hyperthermia & Central Core Disease
    Role: Co-Principal Investigator

    R01AR061370     (RODNEY, GEORGE G)Aug 1, 2012 - Jul 31, 2022
    NIH/NIAMS
    NADPH Oxidase and Autophagic Dysfunction in Duchenne Muscular Dystrophy
    Role: Principal Investigator

    R21NS085208     (RODNEY, GEORGE G)May 15, 2014 - Apr 30, 2016
    NIH/NINDS
    MANGANESE ENHANCED MRI: NON-INVASIVE MEASURE OF PATHOGENESIS OF DYSTROPHINOPATHY
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rodney GG, Pal R, Abo-Zahrah R. Redox regulation of autophagy in skeletal muscle. Free Radic Biol Med. 2016 09; 98:103-112. PMID: 27184957.
      View in: PubMed
    2. Wang Q, Wang W, Wang G, Rodney GG, Wehrens XH. Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):177-84. PMID: 26555638.
      View in: PubMed
    3. Pham K, Pal R, Qu Y, Liu X, Yu H, Shiao SL, Wang X, O'Brian Smith E, Cui X, Rodney GG, Cheng N. Nuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell death. Free Radic Biol Med. 2015 Aug; 85:197-206. PMID: 25975981.
      View in: PubMed
    4. Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL. Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function. Skelet Muscle. 2015; 5:4. PMID: 25717360.
      View in: PubMed
    5. Loehr JA, Abo-Zahrah R, Pal R, Rodney GG. Sphingomyelinase promotes oxidant production and skeletal muscle contractile dysfunction through activation of NADPH oxidase. Front Physiol. 2014; 5:530. PMID: 25653619.
      View in: PubMed
    6. Pal R, Palmieri M, Loehr JA, Li S, Abo-Zahrah R, Monroe TO, Thakur PB, Sardiello M, Rodney GG. Src-dependent impairment of autophagy by oxidative stress in a mouse model of Duchenne muscular dystrophy. Nat Commun. 2014 Jul 16; 5:4425. PMID: 25028121.
      View in: PubMed
    7. Pal R, Monroe TO, Palmieri M, Sardiello M, Rodney GG. Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells. FEBS Lett. 2014 Jan 31; 588(3):472-81. PMID: 24374334.
      View in: PubMed
    8. Pal R, Basu Thakur P, Li S, Minard C, Rodney GG. Real-time imaging of NADPH oxidase activity in living cells using a novel fluorescent protein reporter. PLoS One. 2013; 8(5):e63989. PMID: 23704967.
      View in: PubMed
    9. Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL. AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation. Nat Med. 2012 Jan 08; 18(2):244-51. PMID: 22231556.
      View in: PubMed
    10. Ziman AP, Ward CW, Rodney GG, Lederer WJ, Bloch RJ. Quantitative measurement of Ca²(+) in the sarcoplasmic reticulum lumen of mammalian skeletal muscle. Biophys J. 2010 Oct 20; 99(8):2705-14. PMID: 20959112.
      View in: PubMed
    11. Michaelson LP, Shi G, Ward CW, Rodney GG. Mitochondrial redox potential during contraction in single intact muscle fibers. Muscle Nerve. 2010 Oct; 42(4):522-9. PMID: 20730875.
      View in: PubMed
    12. Rodney GG. Calmodulin in adult mammalian skeletal muscle: localization and effect on sarcoplasmic reticulum Ca2+ release. Am J Physiol Cell Physiol. 2008 May; 294(5):C1288-97. PMID: 18322139.
      View in: PubMed
    13. Ward CW, Rodney GG. Does a lack of RyR3 make mammalian skeletal muscle EC coupling a 'spark-less' affair? J Physiol. 2008 Jan 15; 586(2):313-4. PMID: 18192614.
      View in: PubMed
    14. Brown LD, Rodney GG, Hernández-Ochoa E, Ward CW, Schneider MF. Ca2+ sparks and T tubule reorganization in dedifferentiating adult mouse skeletal muscle fibers. Am J Physiol Cell Physiol. 2007 Mar; 292(3):C1156-66. PMID: 17065203.
      View in: PubMed
    15. Zhang Y, Rodney GG, Schneider MF. Effects of azumolene on Ca2+ sparks in skeletal muscle fibers. J Pharmacol Exp Ther. 2005 Jul; 314(1):94-102. PMID: 15831441.
      View in: PubMed
    16. Rodney GG, Wilson GM, Schneider MF. A calmodulin binding domain of RyR increases activation of spontaneous Ca2+ sparks in frog skeletal muscle. J Biol Chem. 2005 Mar 25; 280(12):11713-22. PMID: 15640144.
      View in: PubMed
    17. Schneider MF, Rodney GG, Ward CW. Local Ca2+ release events in skeletal muscle. J Muscle Res Cell Motil. 2004; 25(8):587-9. PMID: 16118845.
      View in: PubMed
    18. Schneider MF, Rodney GG. Peptide and protein modulation of local Ca2+ release events in permeabilized skeletal muscle fibers. Biol Res. 2004; 37(4):613-6. PMID: 15709689.
      View in: PubMed
    19. Rodney GG, Schneider MF. Calmodulin modulates initiation but not termination of spontaneous Ca2+ sparks in frog skeletal muscle. Biophys J. 2003 Aug; 85(2):921-32. PMID: 12885639.
      View in: PubMed
    20. Xiong LW, Newman RA, Rodney GG, Thomas O, Zhang JZ, Persechini A, Shea MA, Hamilton SL. Lobe-dependent regulation of ryanodine receptor type 1 by calmodulin. J Biol Chem. 2002 Oct 25; 277(43):40862-70. PMID: 12185083.
      View in: PubMed
    21. Rodney GG, Krol J, Williams B, Beckingham K, Hamilton SL. The carboxy-terminal calcium binding sites of calmodulin control calmodulin's switch from an activator to an inhibitor of RYR1. Biochemistry. 2001 Oct 16; 40(41):12430-5. PMID: 11591164.
      View in: PubMed
    22. Pate P, Mochca-Morales J, Wu Y, Zhang JZ, Rodney GG, Serysheva II, Williams BY, Anderson ME, Hamilton SL. Determinants for calmodulin binding on voltage-dependent Ca2+ channels. J Biol Chem. 2000 Dec 15; 275(50):39786-92. PMID: 11005820.
      View in: PubMed
    23. Rodney GG, Moore CP, Williams BY, Zhang JZ, Krol J, Pedersen SE, Hamilton SL. Calcium binding to calmodulin leads to an N-terminal shift in its binding site on the ryanodine Receptor. J Biol Chem. 2001 Jan 19; 276(3):2069-74. PMID: 11035044.
      View in: PubMed
    24. Rodney GG, Williams BY, Strasburg GM, Beckingham K, Hamilton SL. Regulation of RYR1 activity by Ca(2+) and calmodulin. Biochemistry. 2000 Jul 04; 39(26):7807-12. PMID: 10869186.
      View in: PubMed
    25. Moore CP, Rodney G, Zhang JZ, Santacruz-Toloza L, Strasburg G, Hamilton SL. Apocalmodulin and Ca2+ calmodulin bind to the same region on the skeletal muscle Ca2+ release channel. Biochemistry. 1999 Jun 29; 38(26):8532-7. PMID: 10387100.
      View in: PubMed
    26. Zhang JZ, Wu Y, Williams BY, Rodney G, Mandel F, Strasburg GM, Hamilton SL. Oxidation of the skeletal muscle Ca2+ release channel alters calmodulin binding. Am J Physiol. 1999 Jan; 276(1 Pt 1):C46-53. PMID: 9886919.
      View in: PubMed
    27. Bisnett T, Anzueto A, Andrade FH, Rodney GG, Napier WR, Levine SM, Maxwell LC, Mureeba P, Derdak SD, Grisham MB, Jenkinson SG. Effect of nitric oxide synthase inhibitor on diaphragmatic function after resistive loading. Comp Biochem Physiol A Mol Integr Physiol. 1998 Jan; 119(1):185-90. PMID: 11253784.
      View in: PubMed
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