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TODD HEALLEN

Address6770 BERTNER AVE SUITE C330,C1095
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Heallen TR, Martin JF. Hippo Pathway Knockdown Gene Therapy in the Heart. Tex Heart Inst J. 2023 10 17; 50(5). PMID: 37859620; PMCID: PMC10658148.
      Citations:    
    2. Liu S, Tang L, Zhao X, Nguyen B, Heallen TR, Li M, Wang J, Wang J, Martin JF. Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration. Circ Res. 2021 10; 129(8):782-797. PMID: 34424032; PMCID: PMC8513110.
      Citations:    
    3. Liu S, Li K, Wagner Florencio L, Tang L, Heallen TR, Leach JP, Wang Y, Grisanti F, Willerson JT, Perin EC, Zhang S, Martin JF. Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction. Sci Transl Med. 2021 06 30; 13(600). PMID: 34193613; PMCID: PMC9476348.
      Citations:    
    4. Heallen TR, Kadow ZA, Wang J, Martin JF. Determinants of Cardiac Growth and Size. Cold Spring Harb Perspect Biol. 2020 03 02; 12(3). PMID: 31615785; PMCID: PMC7050588.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    5. Heallen TR, Kadow ZA, Kim JH, Wang J, Martin JF. Stimulating Cardiogenesis as a Treatment for Heart Failure. Circ Res. 2019 05 24; 124(11):1647-1657. PMID: 31120819; PMCID: PMC6534162.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    6. Monroe TO, Hill MC, Morikawa Y, Leach JP, Heallen T, Cao S, Krijger PHL, de Laat W, Wehrens XHT, Rodney GG, Martin JF. YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In?Vivo. Dev Cell. 2019 03 25; 48(6):765-779.e7. PMID: 30773489; PMCID: PMC6435425.
      Citations: 62     Fields:    Translation:AnimalsCells
    7. Wang J, Liu S, Heallen T, Martin JF. The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration. Nat Rev Cardiol. 2018 11; 15(11):672-684. PMID: 30111784.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    8. Heallen TR, Martin JF. Heart repair via cardiomyocyte-secreted vesicles. Nat Biomed Eng. 2018 05; 2(5):271-272. PMID: 30936454.
      Citations:    
    9. Leach JP, Heallen T, Zhang M, Rahmani M, Morikawa Y, Hill MC, Segura A, Willerson JT, Martin JF. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature. 2017 10 12; 550(7675):260-264. PMID: 28976966; PMCID: PMC5729743.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    10. Morikawa Y, Heallen T, Leach J, Xiao Y, Martin JF. Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Nature. 2017 07 13; 547(7662):227-231. PMID: 28581498; PMCID: PMC5528853.
      Citations:    
    11. Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF. Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. Nature. 2016 06 02; 534(7605):119-23. PMID: 27251288; PMCID: PMC4999251.
      Citations: 125     Fields:    Translation:AnimalsCells
    12. Morikawa Y, Zhang M, Heallen T, Leach J, Tao G, Xiao Y, Bai Y, Li W, Willerson JT, Martin JF. Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice. Sci Signal. 2015 May 05; 8(375):ra41. PMID: 25943351; PMCID: PMC4442128.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    13. Song S, Ajani JA, Honjo S, Maru DM, Chen Q, Scott AW, Heallen TR, Xiao L, Hofstetter WL, Weston B, Lee JH, Wadhwa R, Sudo K, Stroehlein JR, Martin JF, Hung MC, Johnson RL. Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties. Cancer Res. 2014 Aug 01; 74(15):4170-82. PMID: 24906622; PMCID: PMC4136429.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    14. Heallen T, Morikawa Y, Leach J, Tao G, Willerson JT, Johnson RL, Martin JF. Hippo signaling impedes adult heart regeneration. Development. 2013 Dec; 140(23):4683-90. PMID: 24255096; PMCID: PMC3833428.
      Citations: 192     Fields:    Translation:AnimalsCells
    15. Singh R, Hoogaars WM, Barnett P, Grieskamp T, Rana MS, Buermans H, Farin HF, Petry M, Heallen T, Martin JF, Moorman AF, 't Hoen PA, Kispert A, Christoffels VM, Singh R. Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. Cell Mol Life Sci. 2012 Apr; 69(8):1377-89. PMID: 22130515; PMCID: PMC3314179.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    16. Heallen T, Zhang M, Wang J, Bonilla-Claudio M, Klysik E, Johnson RL, Martin JF. Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science. 2011 Apr 22; 332(6028):458-61. PMID: 21512031; PMCID: PMC3133743.
      Citations: 497     Fields:    Translation:AnimalsCells
    17. Heallen TR, Adams HP, Furuta T, Verbrugghe KJ, Schumacher JM. An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2. Dev Cell. 2008 Oct; 15(4):603-16. PMID: 18854144; PMCID: PMC2582393.
      Citations:    
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