"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 2 | 5 | 7 |
| 2007 | 7 | 4 | 11 |
| 2008 | 4 | 6 | 10 |
| 2009 | 8 | 5 | 13 |
| 2010 | 9 | 3 | 12 |
| 2011 | 12 | 8 | 20 |
| 2012 | 7 | 8 | 15 |
| 2013 | 15 | 17 | 32 |
| 2014 | 13 | 14 | 27 |
| 2015 | 19 | 13 | 32 |
| 2016 | 17 | 10 | 27 |
| 2017 | 13 | 19 | 32 |
| 2018 | 10 | 26 | 36 |
| 2019 | 13 | 18 | 31 |
| 2020 | 6 | 18 | 24 |
| 2021 | 15 | 15 | 30 |
| 2022 | 1 | 18 | 19 |
| 2023 | 6 | 17 | 23 |
| 2024 | 10 | 16 | 26 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells. ACS Synth Biol. 2025 Feb 21; 14(2):384-397.
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DNA methylation profiling at base-pair resolution reveals unique epigenetic features of early-onset colorectal cancer in underrepresented populations. Clin Epigenetics. 2025 Jan 22; 17(1):11.
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Associations of maternal night shift work during pregnancy with DNA methylation in offspring: a meta-analysis in the PACE consortium. Clin Epigenetics. 2025 Jan 22; 17(1):12.
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Key epigenetic and signaling factors in the formation and maintenance of the blood-brain barrier. Elife. 2024 Dec 13; 12.
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Association of exposure to second-hand smoke during childhood with blood DNA methylation. Environ Int. 2025 Jan; 195:109204.
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Transcriptomic and epigenomic signatures distinguish high- and low-risk endotypes for liver tumor development. Environ Mol Mutagen. 2024 Nov; 65(9):351-359.
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The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development. EMBO Rep. 2025 Jan; 26(1):175-199.
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Interplay of Reactive Oxygen Species (ROS) and Epigenetic Remodelling in Cardiovascular Diseases Pathogenesis: A Contemporary Perspective. Front Biosci (Landmark Ed). 2024 Nov 21; 29(11):398.
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Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer. Clin Cancer Res. 2024 Nov 15; 30(22):5166-5179.
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Multiomic and clinical analysis of multiply recurrent meningiomas reveals risk factors, underlying biology, and insights into evolution. Sci Adv. 2024 Oct 25; 10(43):eadn4419.