Interferon Regulatory Factor-1
"Interferon Regulatory Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
| Descriptor ID |
D050856
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| MeSH Number(s) |
D12.644.360.024.302.124 D12.776.157.057.050.124 D12.776.260.108.374 D12.776.260.504.124 D12.776.476.024.385.124 D12.776.930.127.374 D12.776.930.332.124
|
| Concept/Terms |
Interferon Regulatory Factor-1- Interferon Regulatory Factor-1
- Interferon Regulatory Factor 1
- IRF-1 Protein
- IRF 1 Protein
- IREBF1 Transcription Factor
- Transcription Factor, IREBF1
- IREBF1 Protein
- IRF-1 Transcription Factor
- Factor, IRF-1 Transcription
- IRF 1 Transcription Factor
- Transcription Factor, IRF-1
- ISGF1 Transcription Factor
- Factor, ISGF1 Transcription
- Transcription Factor, ISGF1
- Interferon-Stimulated Gene Factor 1
- Interferon Stimulated Gene Factor 1
- MyD32 Protein
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-1".
This graph shows the total number of publications written about "Interferon Regulatory Factor-1" by people in this website by year, and whether "Interferon Regulatory Factor-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-1" by people in Profiles.
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Verteporfin Inhibits PD-L1 through Autophagy and the STAT1-IRF1-TRIM28 Signaling Axis, Exerting Antitumor Efficacy. Cancer Immunol Res. 2020 07; 8(7):952-965.
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Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. Sci Rep. 2018 09 05; 8(1):13225.
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Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4.
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The Effect of Lipopolysaccharide on Noxa Expression Is Mediated through IRF1, 3, and 7. J Microbiol Biotechnol. 2018 Mar 28; 28(3):491-497.
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Promoter Methylation Modulates Indoleamine 2,3-Dioxygenase 1 Induction by Activated T Cells in Human Breast Cancers. Cancer Immunol Res. 2017 04; 5(4):330-344.
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Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy. Oncotarget. 2015 Oct 13; 6(31):31479-92.
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Suppression of IRF4 by IRF1, 3, and 7 in Noxa expression is a necessary event for IFN-?-mediated tumor elimination. Mol Cancer Res. 2011 Oct; 9(10):1356-65.
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Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol. 2012 Jan; 29(1):101-11.
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High glucose up-regulates angiotensin II subtype 2 receptors via interferon regulatory factor-1 in proximal tubule epithelial cells. Mol Cell Biochem. 2010 Nov; 344(1-2):65-71.
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Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. J Exp Med. 2009 Jun 08; 206(6):1227-35.