"Pentacyclic Triterpenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Five-ring derivatives of dammarane having a chair-chair-chair-boat configuration. They include the lupanes, oleananes, amyrins, GLYCYRRHIZIC ACID, and soyasaponins.
| Descriptor ID |
D053978
|
| MeSH Number(s) |
D02.455.849.919.530
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentacyclic Triterpenes".
Below are MeSH descriptors whose meaning is more specific than "Pentacyclic Triterpenes".
This graph shows the total number of publications written about "Pentacyclic Triterpenes" by people in this website by year, and whether "Pentacyclic Triterpenes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pentacyclic Triterpenes" by people in Profiles.
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EpCAM-targeted betulinic acid analogue nanotherapy improves therapeutic efficacy and induces anti-tumorigenic immune response in colorectal cancer tumor microenvironment. J Biomed Sci. 2024 Aug 20; 31(1):81.
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Identification of celastrol as a novel HIV-1 latency reversal agent by an image-based screen. PLoS One. 2021; 16(4):e0244771.
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Genetic and Pharmacological Targeting of Heat Shock Protein 70 in the Mouse Amygdala-Kindling Model. ACS Chem Neurosci. 2019 03 20; 10(3):1434-1444.
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A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer. Pharmacol Res. 2018 03; 129:500-514.
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TGR5 signaling reduces neuroinflammation during hepatic encephalopathy. J Neurochem. 2015 Nov; 135(3):565-76.
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Lamin B1 is a novel therapeutic target of betulinic acid in pancreatic cancer. Clin Cancer Res. 2013 Sep 01; 19(17):4651-61.
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Celastrol suppresses tumor cell growth through targeting an AR-ERG-NF-?B pathway in TMPRSS2/ERG fusion gene expressing prostate cancer. PLoS One. 2013; 8(3):e58391.
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Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo. Cancer Prev Res (Phila). 2012 Apr; 5(4):631-43.
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Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis. Cancer Res. 2011 Aug 01; 71(15):5182-93.
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Lupeol suppresses cisplatin-induced nuclear factor-kappaB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Res. 2007 Sep 15; 67(18):8800-9.