"Oleanolic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.
| Descriptor ID |
D009828
|
| MeSH Number(s) |
D02.455.849.919.530.733 D02.455.849.919.650.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oleanolic Acid".
Below are MeSH descriptors whose meaning is more specific than "Oleanolic Acid".
This graph shows the total number of publications written about "Oleanolic Acid" by people in this website by year, and whether "Oleanolic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Oleanolic Acid" by people in Profiles.
-
Bardoxolone Methyl Ameliorates Chemotherapy-Induced Neuropathic Pain by Activation of Phosphorylated Nuclear Factor Erythroid 2-Related Factor 2 in the Dorsal Root Ganglia. Anesth Analg. 2024 Mar 01; 138(3):664-675.
-
Inhibition of mitochondrial LonP1 protease by allosteric blockade of ATP binding and hydrolysis via CDDO and its derivatives. J Biol Chem. 2022 03; 298(3):101719.
-
Restructuring the Gut Microbiota by Intermittent Fasting Lowers Blood Pressure. Circ Res. 2021 04 30; 128(9):1240-1254.
-
Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF? Signaling. Cancer Res. 2020 05 01; 80(9):1819-1832.
-
Prevention of murine lupus nephritis by targeting multiple signaling axes and oxidative stress using a synthetic triterpenoid. Arthritis Rheumatol. 2014 Nov; 66(11):3129-39.
-
Identification of unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma by a large-scale synthetic lethal RNAi screening. Pigment Cell Melanoma Res. 2013 Jan; 26(1):97-112.
-
Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERa/Sp1-mediated p53 activation. J Cell Physiol. 2012 Oct; 227(10):3363-72.
-
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas. Clin Cancer Res. 2012 Jun 15; 18(12):3396-406.
-
The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives. Blood. 2012 Apr 05; 119(14):3321-9.
-
Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway. Toxicol Appl Pharmacol. 2011 Sep 01; 255(2):176-83.