"Glycyrrhizic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
| Descriptor ID |
D019695
|
| MeSH Number(s) |
D02.455.849.919.530.466
|
| Concept/Terms |
Glycyrrhizic Acid- Glycyrrhizic Acid
- Acid, Glycyrrhizic
- Glycyrrhizinic Acid
- Acid, Glycyrrhizinic
- Glycyrrhizin
|
Below are MeSH descriptors whose meaning is more general than "Glycyrrhizic Acid".
Below are MeSH descriptors whose meaning is more specific than "Glycyrrhizic Acid".
This graph shows the total number of publications written about "Glycyrrhizic Acid" by people in this website by year, and whether "Glycyrrhizic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycyrrhizic Acid" by people in Profiles.
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Glycyrrhizic acid conjugates with amino acid methyl esters target the main protease, exhibiting antiviral activity against wild-type and nirmatrelvir-resistant SARS-CoV-2 variants. Antiviral Res. 2024 07; 227:105920.
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Tubular Epithelial Cell HMGB1 Promotes AKI-CKD Transition by Sensitizing Cycling Tubular Cells to Oxidative Stress: A Rationale for Targeting HMGB1 during AKI Recovery. J Am Soc Nephrol. 2023 03 01; 34(3):394-411.
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The Anti-inflammatory Effects of HMGB1 Blockades in a Mouse Model of Cutaneous Vasculitis. Front Immunol. 2020; 11:2032.
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Role of glucocorticoid in the development of glycyrrhizin-induced hypertension. Clin Exp Hypertens. 1994 Nov; 16(6):761-78.