Nucleoside-Triphosphatase
"Nucleoside-Triphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of nucleoside triphosphates to nucleoside diphosphates. It may also catalyze the hydrolysis of nucleotide triphosphates, diphosphates, thiamine diphosphates and FAD. The nucleoside triphosphate phosphohydrolases I and II are subtypes of the enzyme which are found mostly in viruses.
| Descriptor ID |
D043583
|
| MeSH Number(s) |
D08.811.277.040.465
|
| Concept/Terms |
Nucleoside-Triphosphatase- Nucleoside-Triphosphatase
- Nucleosidetriphosphatase
- Nucleoside Triphosphate Phosphohydrolase
- Phosphohydrolase, Nucleoside Triphosphate
- Triphosphate Phosphohydrolase, Nucleoside
- NTPase
- Nucleoside Triphosphatase
- Triphosphatase, Nucleoside
|
Below are MeSH descriptors whose meaning is more general than "Nucleoside-Triphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Nucleoside-Triphosphatase".
This graph shows the total number of publications written about "Nucleoside-Triphosphatase" by people in this website by year, and whether "Nucleoside-Triphosphatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nucleoside-Triphosphatase" by people in Profiles.
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Identification of affinity-optimized peptide binders of a viral protease for chemical genetic applications. Bioorg Med Chem Lett. 2026 Feb 01; 131:130463.
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Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease. Eur J Med Chem. 2021 Dec 05; 225:113767.
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Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J Med Chem. 2021 03 11; 64(5):2777-2800.
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Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J Am Chem Soc. 2019 05 01; 141(17):6832-6836.
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An Immunocompetent Mouse Model of Zika Virus Infection. Cell Host Microbe. 2018 05 09; 23(5):672-685.e6.
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Grazoprevir plus peginterferon and ribavirin in treatment-naive patients with hepatitis C virus genotype 1 infection: a randomized trial. J Viral Hepat. 2016 Feb; 23(2):80-8.
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Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity. J Virol. 2012 Oct; 86(19):10547-57.
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An overview of emerging therapies for the treatment of chronic hepatitis C. Clin Liver Dis. 2011 Aug; 15(3):515-36.
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Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet. 2010 Aug 28; 376(9742):705-16.
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Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem J. 2006 Jan 15; 393(Pt 2):503-11.