"Apyrase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A calcium-activated enzyme that catalyzes the hydrolysis of ATP to yield AMP and orthophosphate. It can also act on ADP and other nucleoside triphosphates and diphosphates. EC 3.6.1.5.
| Descriptor ID |
D001081
|
| MeSH Number(s) |
D08.811.277.040.050
|
| Concept/Terms |
Apyrase- Apyrase
- ADP Phosphohydrolase
- Phosphohydrolase, ADP
- ADPase
- ATP-ADPase
- ATP ADPase
- ATP-Diphosphatase
- ATP Diphosphatase
- ATP Diphosphohydrolase
- Diphosphohydrolase, ATP
- Adenosine Diphosphatase
- Diphosphatase, Adenosine
|
Below are MeSH descriptors whose meaning is more general than "Apyrase".
Below are MeSH descriptors whose meaning is more specific than "Apyrase".
This graph shows the total number of publications written about "Apyrase" by people in this website by year, and whether "Apyrase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2022 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Apyrase" by people in Profiles.
-
Biallelic Variants in the Ectonucleotidase ENTPD1 Cause a Complex Neurodevelopmental Disorder with Intellectual Disability, Distinct White Matter Abnormalities, and Spastic Paraplegia. Ann Neurol. 2022 08; 92(2):304-321.
-
Recombinant Apyrase (AZD3366) Against Myocardial Reperfusion Injury. Cardiovasc Drugs Ther. 2023 08; 37(4):625-646.
-
Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis. Purinergic Signal. 2019 09; 15(3):375-385.
-
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39. Nat Neurosci. 2019 05; 22(5):729-740.
-
Purinergic signaling during intestinal inflammation. J Mol Med (Berl). 2017 Sep; 95(9):915-925.
-
Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice. J Lipid Res. 2017 07; 58(7):1292-1305.
-
CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease. J Autoimmun. 2016 08; 72:102-12.
-
Effects of chemical inhibitors and apyrase enzyme further document a role for apyrases and extracellular ATP in the opening and closing of stomates in Arabidopsis. Plant Signal Behav. 2013 Nov; 8(11):e26093.
-
Expression of ecto-nucleoside triphosphate diphosphohydrolase1-3 (NTPDase1-3) by cortical astrocytes after exposure to pro-inflammatory factors in vitro. J Mol Neurosci. 2013 Nov; 51(3):871-9.
-
Both the stimulation and inhibition of root hair growth induced by extracellular nucleotides in Arabidopsis are mediated by nitric oxide and reactive oxygen species. Plant Mol Biol. 2010 Nov; 74(4-5):423-35.