"Apyrase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A calcium-activated enzyme that catalyzes the hydrolysis of ATP to yield AMP and orthophosphate. It can also act on ADP and other nucleoside triphosphates and diphosphates. EC 3.6.1.5.
| Descriptor ID |
D001081
|
| MeSH Number(s) |
D08.811.277.040.050
|
| Concept/Terms |
Apyrase- Apyrase
- ADP Phosphohydrolase
- Phosphohydrolase, ADP
- ADPase
- ATP-ADPase
- ATP ADPase
- ATP-Diphosphatase
- ATP Diphosphatase
- ATP Diphosphohydrolase
- Diphosphohydrolase, ATP
- Adenosine Diphosphatase
- Diphosphatase, Adenosine
|
Below are MeSH descriptors whose meaning is more general than "Apyrase".
Below are MeSH descriptors whose meaning is more specific than "Apyrase".
This graph shows the total number of publications written about "Apyrase" by people in this website by year, and whether "Apyrase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Apyrase" by people in Profiles.
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Exploring the Expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study. Pathobiology. 2024; 91(3):205-218.
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Biallelic Variants in the Ectonucleotidase ENTPD1 Cause a Complex Neurodevelopmental Disorder with Intellectual Disability, Distinct White Matter Abnormalities, and Spastic Paraplegia. Ann Neurol. 2022 08; 92(2):304-321.
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Recombinant Apyrase (AZD3366) Against Myocardial Reperfusion Injury. Cardiovasc Drugs Ther. 2023 08; 37(4):625-646.
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Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients. Int J Cancer. 2021 07 15; 149(2):327-336.
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Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration. JCI Insight. 2020 09 03; 5(17).
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Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis. Purinergic Signal. 2019 09; 15(3):375-385.
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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018 11 01; 175(4):998-1013.e20.
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Role of ADP receptors on platelets in the growth of ovarian cancer. Blood. 2017 09 07; 130(10):1235-1242.
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Purinergic signaling during intestinal inflammation. J Mol Med (Berl). 2017 Sep; 95(9):915-925.
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Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice. J Lipid Res. 2017 07; 58(7):1292-1305.