"Liver Cirrhosis, Biliary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
| Descriptor ID |
D008105
|
| MeSH Number(s) |
C06.130.120.135.250.250 C06.552.150.250 C06.552.630.400
|
| Concept/Terms |
Biliary Cirrhosis, Secondary- Biliary Cirrhosis, Secondary
- Cirrhosis, Secondary Biliary
- Liver Cirrhosis, Obstructive
- Obstructive Liver Cirrhosis
- Secondary Biliary Cirrhosis
Biliary Cirrhosis, Primary- Biliary Cirrhosis, Primary
- Biliary Cirrhosis, Primary, 1
- Cholangitis, Chronic Nonsuppurative Destructive
- Primary Biliary Cirrhosis
|
Below are MeSH descriptors whose meaning is more general than "Liver Cirrhosis, Biliary".
Below are MeSH descriptors whose meaning is more specific than "Liver Cirrhosis, Biliary".
This graph shows the total number of publications written about "Liver Cirrhosis, Biliary" by people in this website by year, and whether "Liver Cirrhosis, Biliary" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 1 | 3 |
| 2011 | 2 | 0 | 2 |
| 2012 | 4 | 0 | 4 |
| 2013 | 3 | 0 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 9 | 1 | 10 |
| 2016 | 4 | 0 | 4 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 2 | 0 | 2 |
| 2023 | 3 | 0 | 3 |
| 2024 | 5 | 0 | 5 |
| 2026 | 3 | 0 | 3 |
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Below are the most recent publications written about "Liver Cirrhosis, Biliary" by people in Profiles.
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International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. Nat Commun. 2015 Sep 22; 6:8019.
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Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. Hum Mol Genet. 2012 Dec 01; 21(23):5209-21.
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Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. Nat Genet. 2010 Aug; 42(8):655-7.
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Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. Nat Genet. 2010 Aug; 42(8):658-60.
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Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med. 2009 Jun 11; 360(24):2544-55.
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CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population. Arthritis Rheum. 2009 Apr; 60(4):931-7.
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Lipoprotein-X reduces LDL atherogenicity in primary biliary cirrhosis by preventing LDL oxidation. J Lipid Res. 2004 Nov; 45(11):2116-22.
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Epidermal growth factor is decreased in liver of rats with biliary cirrhosis but does not act as paracrine growth factor immediately after hepatectomy. J Hepatol. 2000 Aug; 33(2):275-81.
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Primary hepatic low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) associated with primary biliary cirrhosis. Mod Pathol. 1998 Apr; 11(4):404-10.