Diacylglycerol O-Acyltransferase
"Diacylglycerol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC 2.3.1.124.
| Descriptor ID |
D051048
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| MeSH Number(s) |
D08.811.913.050.387
|
| Concept/Terms |
Diacylglycerol O-Acyltransferase- Diacylglycerol O-Acyltransferase
- Diacylglycerol O Acyltransferase
- O-Acyltransferase, Diacylglycerol
- DAGAT Enzyme
- Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol Acyltransferase
- A-sn-1,2-Diacylglycerol Acyltransferase, Palmitoyl-Coenzyme
- Acyltransferase, Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol
- Palmitoyl Coenzyme A sn 1,2 Diacylglycerol Acyltransferase
- Diacylglycerol O-Acyltransferase 1
- Diacylglycerol O Acyltransferase 1
- O-Acyltransferase 1, Diacylglycerol
- Diglyceride Acyltransferase
- Acyltransferase, Diglyceride
- Palmitoyl-CoA-sn-1,2-Diacylglycerol Acyltransferase
- Acyltransferase, Palmitoyl-CoA-sn-1,2-Diacylglycerol
- Palmitoyl CoA sn 1,2 Diacylglycerol Acyltransferase
- Acyl-Coenzyme A Diacyl-glycerol Acyltransferase
- Acyl Coenzyme A Diacyl glycerol Acyltransferase
- Diacylglycerol Acyltransferase
- Acyltransferase, Diacylglycerol
|
Below are MeSH descriptors whose meaning is more general than "Diacylglycerol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol O-Acyltransferase".
This graph shows the total number of publications written about "Diacylglycerol O-Acyltransferase" by people in this website by year, and whether "Diacylglycerol O-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Diacylglycerol O-Acyltransferase" by people in Profiles.
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Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nat Commun. 2024 Jan 02; 15(1):79.
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Rotavirus-mediated DGAT1 degradation: A pathophysiological mechanism of viral-induced malabsorptive diarrhea. Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2302161120.
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Structure and mechanism of human diacylglycerol O-acyltransferase?1. Nature. 2020 05; 581(7808):329-332.
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Dietary Macronutrient Composition Determines the Contribution of DGAT1 to Alcoholic Steatosis. Alcohol Clin Exp Res. 2018 12; 42(12):2298-2312.
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Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPa-p300/DGAT1 pathway. Aging Cell. 2018 02; 17(1).
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Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis. Cell Rep. 2013 Mar 28; 3(3):831-43.
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Triacylglycerol biosynthesis occurs via the glycerol-3-phosphate pathway in the insect Rhodnius prolixus. Biochim Biophys Acta. 2012 Dec; 1821(12):1462-71.
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Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein. Mol Cell Biol. 2006 Feb; 26(3):1063-76.