"Stearoyl-CoA Desaturase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of oleoyl-CoA, A, and water from stearoyl-CoA, AH2, and oxygen where AH2 is an unspecified hydrogen donor.
| Descriptor ID |
D013230
|
| MeSH Number(s) |
D08.811.682.690.708.392.625
|
| Concept/Terms |
Stearoyl-CoA Desaturase- Stearoyl-CoA Desaturase
- Desaturase, Stearoyl-CoA
- Stearoyl CoA Desaturase
- Stearate Desaturase
- Desaturase, Stearate
- Stearyl-CoA Desaturase
- Desaturase, Stearyl-CoA
- Stearyl CoA Desaturase
- delta-9 Desaturase
- Desaturase, delta-9
- delta 9 Desaturase
|
Below are MeSH descriptors whose meaning is more general than "Stearoyl-CoA Desaturase".
Below are MeSH descriptors whose meaning is more specific than "Stearoyl-CoA Desaturase".
This graph shows the total number of publications written about "Stearoyl-CoA Desaturase" by people in this website by year, and whether "Stearoyl-CoA Desaturase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Stearoyl-CoA Desaturase" by people in Profiles.
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Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages. mBio. 2023 08 31; 14(4):e0092523.
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Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1. J Biol Chem. 2023 07; 299(7):104897.
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Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase. J Mol Biol. 2020 08 21; 432(18):5152-5161.
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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity. Cell Death Differ. 2020 01; 27(1):329-344.
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Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature. 2019 02; 566(7744):403-406.
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Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity. Stem Cells. 2018 10; 36(10):1603-1616.
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Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes. Lipids. 2017 Dec; 52(12):969-980.
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Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6. Gastroenterology. 2017 05; 152(6):1477-1491.
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X-ray structure of a mammalian stearoyl-CoA desaturase. Nature. 2015 Aug 13; 524(7564):252-6.
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Human breast cancer tissues contain abundant phosphatidylcholine(36:1) with high stearoyl-CoA desaturase-1 expression. PLoS One. 2013; 8(4):e61204.