"Stearoyl-CoA Desaturase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of oleoyl-CoA, A, and water from stearoyl-CoA, AH2, and oxygen where AH2 is an unspecified hydrogen donor.
| Descriptor ID |
D013230
|
| MeSH Number(s) |
D08.811.682.690.708.392.625
|
| Concept/Terms |
Stearoyl-CoA Desaturase- Stearoyl-CoA Desaturase
- Desaturase, Stearoyl-CoA
- Stearoyl CoA Desaturase
- Stearate Desaturase
- Desaturase, Stearate
- Stearyl-CoA Desaturase
- Desaturase, Stearyl-CoA
- Stearyl CoA Desaturase
- delta-9 Desaturase
- Desaturase, delta-9
- delta 9 Desaturase
|
Below are MeSH descriptors whose meaning is more general than "Stearoyl-CoA Desaturase".
Below are MeSH descriptors whose meaning is more specific than "Stearoyl-CoA Desaturase".
This graph shows the total number of publications written about "Stearoyl-CoA Desaturase" by people in this website by year, and whether "Stearoyl-CoA Desaturase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Stearoyl-CoA Desaturase" by people in Profiles.
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Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages. mBio. 2023 08 31; 14(4):e0092523.
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Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1. J Biol Chem. 2023 07; 299(7):104897.
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Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase. J Mol Biol. 2020 08 21; 432(18):5152-5161.
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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity. Cell Death Differ. 2020 01; 27(1):329-344.
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Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes. Lipids. 2017 Dec; 52(12):969-980.
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Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people. Mol Nutr Food Res. 2016 12; 60(12):2642-2653.
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X-ray structure of a mammalian stearoyl-CoA desaturase. Nature. 2015 Aug 13; 524(7564):252-6.
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The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis. Oncogene. 2015 Mar 26; 34(13):1718-28.
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Sterculic oil, a natural inhibitor of SCD1, improves the metabolic state of obese OLETF rats. Obesity (Silver Spring). 2013 Feb; 21(2):344-52.
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Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice. J Obes. 2013; 2013:296537.