Serine C-Palmitoyltransferase
"Serine C-Palmitoyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
Descriptor ID |
D051102
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MeSH Number(s) |
D08.811.913.050.668
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Concept/Terms |
Serine C-Palmitoyltransferase- Serine C-Palmitoyltransferase
- C-Palmitoyltransferase, Serine
- Serine C Palmitoyltransferase
- Serine Palmitoyltransferase
- Palmitoyltransferase, Serine
- Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating)
- Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating)
Long Chain Base Biosynthesis Protein 2- Long Chain Base Biosynthesis Protein 2
- Serine-Palmitoyl-CoA Transferase 2
- Serine Palmitoyl CoA Transferase 2
- Transferase 2, Serine-Palmitoyl-CoA
- Serine Palmitoyltransferase 2
- Palmitoyltransferase 2, Serine
- Serine Palmitoyltransferase, Long Chain Base Subunit 2
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Below are MeSH descriptors whose meaning is more general than "Serine C-Palmitoyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Serine C-Palmitoyltransferase".
This graph shows the total number of publications written about "Serine C-Palmitoyltransferase" by people in this website by year, and whether "Serine C-Palmitoyltransferase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine C-Palmitoyltransferase" by people in Profiles.
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SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia. Brain. 2023 04 19; 146(4):1420-1435.
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Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics. J Am Heart Assoc. 2017 12 29; 7(1).
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Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18; 12(7):1169-83.
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Caenorhabditis elegans pathways that surveil and defend mitochondria. Nature. 2014 Apr 17; 508(7496):406-10.