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DAMIAN YOUNG

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
DivisionPharmacology
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Biochemistry & Molecular Biology
    DivisionBiochemistry & Molecular Biology

    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pathology & Immunology
    DivisionPathology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Boyd SR, Chang L, Rezende WC, Raji IO, Kandel P, Holmes SL, Young DW. Design and Applications of Bifunctional Small Molecules in Biology. Biochim Biophys Acta Proteins Proteom. 2020 Aug 29; 140534. PMID: 32871274.
      View in: PubMed
    2. Li F, MacKenzie KR, Jain P, Santini C, Young DW, Matzuk MM. Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes†. Biol Reprod. 2020 Aug 04; 103(2):427-436. PMID: 32285106.
      View in: PubMed
    3. Sarrion-Perdigones A, Chang L, Gonzalez Y, Gallego-Flores T, Young DW, Venken KJT. Simultaneous Examination of Cellular Pathways using Multiplex Hextuple Luciferase Assaying. Curr Protoc Mol Biol. 2020 06; 131(1):e122. PMID: 32539239.
      View in: PubMed
    4. Monty OBC, Nyshadham P, Bohren KM, Palaniappan M, Matzuk MM, Young DW, Simmons N. Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries. ACS Comb Sci. 2020 02 10; 22(2):80-88. PMID: 31913011.
      View in: PubMed
    5. Sarrion-Perdigones A, Chang L, Gonzalez Y, Gallego-Flores T, Young DW, Venken KJT. Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying. Nat Commun. 2019 12 13; 10(1):5710. PMID: 31836712.
      View in: PubMed
    6. Boyd SR, Young DW. Max-imizing the Attenuation of Myc Using Small Molecules. Trends Pharmacol Sci. 2019 09; 40(9):608-612. PMID: 31280901.
      View in: PubMed
    7. Jain P, Raji IO, Chamakuri S, MacKenzie KR, Ebright BT, Santini C, Young DW. Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 05 17; 84(10):6040-6064. PMID: 30848904.
      View in: PubMed
    8. Chamakuri S, Jain P, Guduru SRK, Arney JW, MacKenzie KR, Santini C, Young DW. Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 Apr 05; 84(7):4575. PMID: 30855144.
      View in: PubMed
    9. Reddy Guduru SK, Chamakuri S, Raji IO, MacKenzie KR, Santini C, Young DW. Synthesis of Enantiomerically Pure 3-Substituted Piperazine-2-acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 10 05; 83(19):11777-11793. PMID: 30180575.
      View in: PubMed
    10. Chamakuri S, Jain P, Reddy Guduru SK, Arney JW, MacKenzie KR, Santini C, Young DW. Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 06 15; 83(12):6541-6555. PMID: 29751727.
      View in: PubMed
    11. Wang Y, Wach JY, Sheehan P, Zhong C, Zhan C, Harris R, Almo SC, Bishop J, Haggarty SJ, Ramek A, Berry KN, O'Herin C, Koehler AN, Hung AW, Young DW. Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3ß. ACS Med Chem Lett. 2016 Sep 08; 7(9):852-6. PMID: 27660690.
      View in: PubMed
    12. Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chem Biol. 2013 Dec 19; 20(12):1513-22. PMID: 24290880.
      View in: PubMed
    13. Wang Y, Jimenez M, Sheehan P, Zhong C, Hung AW, Tam CP, Young DW. Selective access to trisubstituted macrocyclic E- and Z-alkenes from the ring-closing metathesis of vinylsiloxanes. Org Lett. 2013 Mar 15; 15(6):1218-21. PMID: 23448432.
      View in: PubMed
    14. Zhong C, Wang Y, Hung AW, Schreiber SL, Young DW. Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts. Org Lett. 2011 Oct 21; 13(20):5556-9. PMID: 21916463.
      View in: PubMed
    15. Pandya BA, Dandapani S, Duvall JR, Rowley A, Mulrooney CA, Ryba T, Dombrowski M, Harton M, Young DW, Marcaurelle LA. Practical asymmetric synthesis of ß-hydroxy ?-amino acids via complimentary aldol reactions. Tetrahedron. 2011 Aug 26; 67(34):6131-6137. PMID: 21822337.
      View in: PubMed
    16. Wang Y, Jimenez M, Hansen AS, Raiber EA, Schreiber SL, Young DW. Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group. J Am Chem Soc. 2011 Jun 22; 133(24):9196-9. PMID: 21557625.
      View in: PubMed
    17. Hung AW, Ramek A, Wang Y, Kaya T, Wilson JA, Clemons PA, Young DW. Route to three-dimensional fragments using diversity-oriented synthesis. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):6799-804. PMID: 21482811.
      View in: PubMed
    18. Marcaurelle LA, Comer E, Dandapani S, Duvall JR, Gerard B, Kesavan S, Lee MD, Liu H, Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A, Ryba TD, Suh BC, Wei J, Young DW, Akella LB, Ross NT, Zhang YL, Fass DM, Reis SA, Zhao WN, Haggarty SJ, Palmer M, Foley MA. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. J Am Chem Soc. 2010 Dec 01; 132(47):16962-76. PMID: 21067169.
      View in: PubMed
    19. Dancík V, Seiler KP, Young DW, Schreiber SL, Clemons PA. Distinct biological network properties between the targets of natural products and disease genes. J Am Chem Soc. 2010 Jul 14; 132(27):9259-61. PMID: 20565092.
      View in: PubMed
    20. Young DW. Synthetic chemistry: An upfront investment. Nat Chem Biol. 2010 Mar; 6(3):174-175. PMID: 20154664.
      View in: PubMed
    21. Kelly AR, Wei J, Kesavan S, Marié JC, Windmon N, Young DW, Marcaurelle LA. Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings. Org Lett. 2009 Jun 04; 11(11):2257-60. PMID: 19473044.
      View in: PubMed
    22. Young DW, Comins DL. Tandem directed lithiations of N-Boc-1,2-dihydropyridines toward highly functionalized 2,3-dihydro-4-pyridones. Org Lett. 2005 Dec 08; 7(25):5661-4. PMID: 16321016.
      View in: PubMed
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