"ADAMTS Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of ADAM proteases that are distinguished by the presence of one or more THROMBOSPONDIN type-1 repeats (TSRs). These are three-strand motifs that contain characteristic TRYPTOPHAN, ARGININE, and CYSTEINE residues respectively. In contrast to ADAM proteins, which reside on CELL MEMBRANES, ADAMTS proteases are secreted and function in the EXTRACELLULAR MATRIX.
| Descriptor ID |
D000071096
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.500 D09.400.430.500.500 D12.776.395.033.500 D12.776.860.300.085
|
| Concept/Terms |
ADAMTS Proteins- ADAMTS Proteins
- Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins
- ADAMTS Proteases
|
Below are MeSH descriptors whose meaning is more general than "ADAMTS Proteins".
Below are MeSH descriptors whose meaning is more specific than "ADAMTS Proteins".
This graph shows the total number of publications written about "ADAMTS Proteins" by people in this website by year, and whether "ADAMTS Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "ADAMTS Proteins" by people in Profiles.
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Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. Br J Haematol. 2023 04; 201(2):343-352.
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Biallelic variants in ADAMTS15 cause a novel form of distal arthrogryposis. Genet Med. 2022 10; 24(10):2187-2193.
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Biallelic mutation of FBXL7 suggests a novel form of Hennekam syndrome. Am J Med Genet A. 2020 01; 182(1):189-194.
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Identification of Novel Autoantibodies Associated With Psoriatic Arthritis. Arthritis Rheumatol. 2019 06; 71(6):941-951.
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Genetic variants in the metzincin metallopeptidase family genes predict melanoma survival. Mol Carcinog. 2018 Jan; 57(1):22-31.
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Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
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Global gene profiling of aging lungs in Atp8b1 mutant mice. Aging (Albany NY). 2016 09 29; 8(9):2232-2252.
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Genetics of premature ovarian failure. Curr Opin Obstet Gynecol. 2015 Jun; 27(3):167-74.
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Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res. 2010 Nov; 8(11):1513-25.
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A homozygous mutation in ADAMTSL4 causes autosomal-recessive isolated ectopia lentis. Am J Hum Genet. 2009 Feb; 84(2):274-8.