"ADAMTS4 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ADAMTS protease similar to ADAMTS5 PROTEIN. It contains a single C-terminal thrombospondin (TS) motif and cleaves AGGRECAN in CARTILAGE. It may also be involved in the destruction of aggrecan in ARTHRITIS.
| Descriptor ID |
D000071121
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.500.844 D09.400.430.500.500.844 D12.776.395.033.500.844 D12.776.860.300.085.844
|
| Concept/Terms |
ADAMTS4 Protein- ADAMTS4 Protein
- Aggrecanase-1
- Aggrecanase 1
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
- ADAMTS-4 Protein
- ADAMTS 4 Protein
|
Below are MeSH descriptors whose meaning is more general than "ADAMTS4 Protein".
Below are MeSH descriptors whose meaning is more specific than "ADAMTS4 Protein".
This graph shows the total number of publications written about "ADAMTS4 Protein" by people in this website by year, and whether "ADAMTS4 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "ADAMTS4 Protein" by people in Profiles.
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Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice. Sci Rep. 2017 09 27; 7(1):12351.
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ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections. Ann Thorac Surg. 2013 Feb; 95(2):570-7.
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Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Dev Dyn. 2011 Jul; 240(7):1806-14.
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Regulated expression of ADAMTS family members in follicles and cumulus oocyte complexes: evidence for specific and redundant patterns during ovulation. Biol Reprod. 2005 May; 72(5):1241-55.