Adenylyl Cyclase Inhibitors

"Adenylyl Cyclase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Compounds that bind to and inhibit the action of ADENYLYL CYCLASES.

Descriptor ID	D000067956
MeSH Number(s)	D27.505.519.389.108
Concept/Terms	Adenylyl Cyclase Inhibitors Adenylyl Cyclase Inhibitors Cyclase Inhibitors, Adenylyl Inhibitors, Adenylyl Cyclase Adenylate Cyclase Inhibitors Cyclase Inhibitors, Adenylate Inhibitors, Adenylate Cyclase

Below are MeSH descriptors whose meaning is more general than "Adenylyl Cyclase Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Adenylyl Cyclase Inhibitors [D27.505.519.389.108]

Below are MeSH descriptors whose meaning is related to "Adenylyl Cyclase Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Adenylyl Cyclase Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adenylyl Cyclase Inhibitors" by people in this website by year, and whether "Adenylyl Cyclase Inhibitors" was a major or minor topic of these publications.

Bar chart showing 5 publications over 4 distinct years, with a maximum of 2 publications in 2003

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1998	1	1
2003	2	2
2006	1	1
2007	1	1

Below are the most recent publications written about "Adenylyl Cyclase Inhibitors" by people in Profiles.

Schein CH, Chen D, Ma L, Kanalas JJ, Gao J, Jimenez ME, Sower LE, Walter MA, Gilbertson SR, Peterson JW. Pharmacophore selection and redesign of non-nucleotide inhibitors of anthrax edema factor. Toxins (Basel). 2012 Nov 08; 4(11):1288-300.

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Chen D, Ma L, Kanalas JJ, Gao J, Pawlik J, Jimenez ME, Walter MA, Peterson JW, Gilbertson SR, Schein CH. Structure-based redesign of an edema toxin inhibitor. Bioorg Med Chem. 2012 Jan 01; 20(1):368-76.

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Moen ST, Blumentritt CA, Slater TM, Patel SD, Tutt CB, Estrella-Jimenez ME, Pawlik J, Sower L, Popov VL, Schein CH, Gilbertson SR, Peterson JW, Torres AG. Testing the efficacy and toxicity of adenylyl cyclase inhibitors against enteric pathogens using in vitro and in vivo models of infection. Infect Immun. 2010 Apr; 78(4):1740-9.

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Kots AY, Choi BK, Estrella-Jimenez ME, Warren CA, Gilbertson SR, Guerrant RL, Murad F. Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8440-5.

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Ross GR, Yallampalli U, Yallampalli C. Cyclic AMP-independent CGRP8-37-sensitive receptors mediate adrenomedullin-induced decrease of CaCl2-contraction in pregnant rat mesenteric artery. J Vasc Res. 2008; 45(1):33-44.

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Singh U, Devaraj S, Dasu MR, Ciobanu D, Reusch J, Jialal I. C-reactive protein decreases interleukin-10 secretion in activated human monocyte-derived macrophages via inhibition of cyclic AMP production. Arterioscler Thromb Vasc Biol. 2006 Nov; 26(11):2469-75.

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Gangula PR, Thota C, Wimalawansa SJ, Bukoski RD, Yallampalli C. Mechanisms involved in calcitonin gene-related Peptide-induced relaxation in pregnant rat uterine artery. Biol Reprod. 2003 Nov; 69(5):1635-41.

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Salim S, Sinnarajah S, Kehrl JH, Dessauer CW. Identification of RGS2 and type V adenylyl cyclase interaction sites. J Biol Chem. 2003 May 02; 278(18):15842-9.

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Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7.

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Porta R, De Santis A, Esposito C, Draetta GF, Di Donato A, Illiano G. Inhibition of adenylate cyclase by transglutaminase-catalyzed reactions in pigeon erythrocyte ghosts. Biochem Biophys Res Commun. 1986 Jul 31; 138(2):596-603.

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