Receptors, Metabotropic Glutamate
"Receptors, Metabotropic Glutamate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action.
| Descriptor ID |
D018094
|
| MeSH Number(s) |
D12.776.543.750.695.450 D12.776.543.750.720.200.450.500
|
| Concept/Terms |
Receptors, Metabotropic Glutamate- Receptors, Metabotropic Glutamate
- Metabotropic Glutamate Receptor
- Glutamate Receptor, Metabotropic
- Receptor, Metabotropic Glutamate
- Metabotropic Glutamate Receptors
- Receptors, Glutamate, Metabotropic
- Glutamate Receptors, Metabotropic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Metabotropic Glutamate".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Metabotropic Glutamate".
This graph shows the total number of publications written about "Receptors, Metabotropic Glutamate" by people in this website by year, and whether "Receptors, Metabotropic Glutamate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 3 | 5 |
| 2010 | 4 | 0 | 4 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 5 | 0 | 5 |
| 2014 | 4 | 0 | 4 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Metabotropic Glutamate" by people in Profiles.
-
Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions. J Biol Chem. 2023 04; 299(4):103030.
-
The mGluR6 ligand-binding domain, but not the C-terminal domain, is required for synaptic localization in retinal ON-bipolar cells. J Biol Chem. 2021 12; 297(6):101418.
-
Group III metabotropic glutamate receptors regulate hypothalamic presympathetic neurons through opposing presynaptic and postsynaptic actions in hypertension. Neuropharmacology. 2020 09 01; 174:108159.
-
Biallelic GRM7 variants cause epilepsy, microcephaly, and cerebral atrophy. Ann Clin Transl Neurol. 2020 05; 7(5):610-627.
-
mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors. Nat Neurosci. 2018 06; 21(6):799-802.
-
Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer. Oncotarget. 2017 Jul 25; 8(30):49275-49292.
-
Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017 06 14; 353:58-75.
-
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain. Mol Pain. 2017 01; 13:1744806917697009.
-
Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption. Biol Psychiatry. 2016 Mar 15; 79(6):443-51.
-
Activation of group II metabotropic glutamate receptors blocks zinc release from hippocampal mossy fibers. Biol Res. 2014 Dec 18; 47:73.