Cholinesterase Inhibitors
"Cholinesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Descriptor ID |
D002800
|
MeSH Number(s) |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
|
Concept/Terms |
Cholinesterase Inhibitors- Cholinesterase Inhibitors
- Inhibitors, Cholinesterase
- Anticholinesterase Drugs
- Drugs, Anticholinesterase
- Anticholinesterases
- Anticholinesterase Agents
- Agents, Anticholinesterase
- Anti-Cholinesterases
- Anti Cholinesterases
|
Below are MeSH descriptors whose meaning is more general than "Cholinesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Inhibitors".
This graph shows the total number of publications written about "Cholinesterase Inhibitors" by people in this website by year, and whether "Cholinesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
1998 | 5 | 0 | 5 |
1999 | 3 | 0 | 3 |
2001 | 3 | 1 | 4 |
2002 | 0 | 1 | 1 |
2003 | 3 | 1 | 4 |
2004 | 1 | 2 | 3 |
2005 | 5 | 0 | 5 |
2006 | 2 | 2 | 4 |
2007 | 1 | 3 | 4 |
2008 | 4 | 1 | 5 |
2009 | 3 | 4 | 7 |
2010 | 0 | 1 | 1 |
2011 | 2 | 0 | 2 |
2012 | 3 | 1 | 4 |
2013 | 5 | 0 | 5 |
2014 | 1 | 0 | 1 |
2015 | 2 | 2 | 4 |
2016 | 1 | 0 | 1 |
2017 | 2 | 0 | 2 |
2018 | 0 | 2 | 2 |
2019 | 5 | 1 | 6 |
2021 | 2 | 4 | 6 |
2022 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholinesterase Inhibitors" by people in Profiles.
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Update on the Diagnosis and Management of Acute Colonic Pseudo-obstruction (ACPO). Curr Gastroenterol Rep. 2023 Sep; 25(9):191-197.
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Risk of Serious Adverse Events Associated With Individual Cholinesterase Inhibitors Use in Older Adults With Dementia: A Population-Based Cohort Study. Drugs Aging. 2022 06; 39(6):453-465.
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Risk of overactive bladder associated with cholinesterase inhibitors in dementia. J Am Geriatr Soc. 2022 03; 70(3):820-830.
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Antimuscarinic Cascade Across Individual Cholinesterase Inhibitors in Older Adults with Dementia. Drugs Aging. 2021 07; 38(7):593-602.
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a7-Acetylcholine Receptor Signaling Reduces Neuroinflammation After Subarachnoid Hemorrhage in Mice. Neurotherapeutics. 2021 07; 18(3):1891-1904.
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Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study. Drugs Aging. 2021 06; 38(6):493-502.
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Rivastigmine Transdermal Patch Treatment for Moderate to Severe Cognitive Impairment in Veterans with Traumatic Brain Injury (RiVET Study): A Randomized Clinical Trial. J Neurotrauma. 2021 07 15; 38(14):1943-1952.
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Pediatric Autoimmune Ocular Myasthenia Gravis: Evaluation of Presentation and Treatment Outcomes in a Large Cohort. Pediatr Neurol. 2021 05; 118:12-19.
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Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur J Med Chem. 2020 Dec 01; 207:112761.
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American Society for Gastrointestinal Endoscopy guideline on the role of endoscopy in the management of acute colonic pseudo-obstruction and colonic volvulus. Gastrointest Endosc. 2020 02; 91(2):228-235.