Cholinesterase Reactivators
"Cholinesterase Reactivators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.
| Descriptor ID |
D002801
|
| MeSH Number(s) |
D27.505.519.405.347 D27.505.519.625.120.400 D27.505.696.577.120.400
|
| Concept/Terms |
Organophosphate Insecticide Antagonists- Organophosphate Insecticide Antagonists
- Antagonists, Organophosphate Insecticide
- Insecticide Antagonists, Organophosphate
- Insecticides, Organophosphate, Antagonists
|
Below are MeSH descriptors whose meaning is more general than "Cholinesterase Reactivators".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Reactivators".
This graph shows the total number of publications written about "Cholinesterase Reactivators" by people in this website by year, and whether "Cholinesterase Reactivators" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholinesterase Reactivators" by people in Profiles.
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4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase. ACS Chem Neurosci. 2024 05 01; 15(9):1813-1827.
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Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats. Toxicol Appl Pharmacol. 2022 07 01; 446:116046.
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Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX. Chem Biol Interact. 2016 Nov 25; 259(Pt B):154-159.
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Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics. Arch Biochem Biophys. 2016 Jan 15; 590:72-81.
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Novel oximes as blood-brain barrier penetrating cholinesterase reactivators. Chem Biol Interact. 2010 Sep 06; 187(1-3):199-206.