"Binding Sites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a macromolecule that directly participate in its specific combination with another molecule.
| Descriptor ID |
D001665
|
| MeSH Number(s) |
G02.111.570.120
|
| Concept/Terms |
Binding Sites- Binding Sites
- Site, Binding
- Sites, Binding
- Binding Site
- Combining Site
- Combining Sites
- Site, Combining
- Sites, Combining
|
Below are MeSH descriptors whose meaning is more general than "Binding Sites".
Below are MeSH descriptors whose meaning is more specific than "Binding Sites".
This graph shows the total number of publications written about "Binding Sites" by people in this website by year, and whether "Binding Sites" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 30 | 31 |
| 1997 | 0 | 42 | 42 |
| 1998 | 0 | 18 | 18 |
| 1999 | 0 | 25 | 25 |
| 2000 | 0 | 30 | 30 |
| 2001 | 0 | 29 | 29 |
| 2002 | 1 | 37 | 38 |
| 2003 | 0 | 41 | 41 |
| 2004 | 1 | 34 | 35 |
| 2005 | 1 | 31 | 32 |
| 2006 | 1 | 35 | 36 |
| 2007 | 0 | 22 | 22 |
| 2008 | 0 | 18 | 18 |
| 2009 | 1 | 27 | 28 |
| 2010 | 0 | 32 | 32 |
| 2011 | 0 | 25 | 25 |
| 2012 | 0 | 25 | 25 |
| 2013 | 3 | 28 | 31 |
| 2014 | 0 | 16 | 16 |
| 2015 | 1 | 24 | 25 |
| 2016 | 0 | 37 | 37 |
| 2017 | 1 | 32 | 33 |
| 2018 | 1 | 34 | 35 |
| 2019 | 1 | 31 | 32 |
| 2020 | 1 | 19 | 20 |
| 2021 | 0 | 27 | 27 |
| 2022 | 0 | 10 | 10 |
| 2023 | 0 | 8 | 8 |
| 2024 | 0 | 10 | 10 |
| 2025 | 0 | 10 | 10 |
| 2026 | 0 | 4 | 4 |
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Below are the most recent publications written about "Binding Sites" by people in Profiles.
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Exploring the effect of disease causing mutations in metal binding sites of human ARSA in metachromatic leukodystrophy. Adv Protein Chem Struct Biol. 2024; 141:203-221.
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CspZ FH-Binding Sites as Epitopes Promote Antibody-Mediated Lyme Borreliae Clearance. Infect Immun. 2022 07 21; 90(7):e0006222.
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Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP. Mol Cell. 2022 05 05; 82(9):1708-1723.e10.
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Pan-ebolavirus protective therapy by two multifunctional human antibodies. Cell. 2021 10 28; 184(22):5593-5607.e18.
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Durable SARS-CoV-2 B cell immunity after mild or severe disease. J Clin Invest. 2021 04 01; 131(7).
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Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proc Natl Acad Sci U S A. 2021 03 02; 118(9).
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Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III. Cell Biochem Biophys. 2021 Jun; 79(2):201-219.
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KPC-2 ?-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate. J Biol Chem. 2021 Jan-Jun; 296:100155.
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Transcription Factor PLAGL1 Is Associated with Angiogenic Gene Expression in the Placenta. Int J Mol Sci. 2020 Nov 06; 21(21).
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Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host Microbe. 2020 11 11; 28(5):699-711.e7.