"Actinin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein factor that regulates the length of R-actin. It is chemically similar, but immunochemically distinguishable from actin.
| Descriptor ID |
D000185
|
| MeSH Number(s) |
D05.750.078.730.248 D12.776.210.500.095 D12.776.220.525.250
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Actinin".
Below are MeSH descriptors whose meaning is more specific than "Actinin".
This graph shows the total number of publications written about "Actinin" by people in this website by year, and whether "Actinin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Actinin" by people in Profiles.
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Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing. PLoS One. 2016; 11(12):e0167467.
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Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity. PLoS One. 2014; 9(4):e96395.
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ZASP interacts with the mechanosensing protein Ankrd2 and p53 in the signalling network of striated muscle. PLoS One. 2014; 9(3):e92259.
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Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med. 2006 Dec; 3(12):e516.
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Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 05; 282(1):467-77.
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A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15014-9.
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Pathological shear stress directly regulates platelet alphaIIbbeta3 signaling. Am J Physiol Cell Physiol. 2006 Dec; 291(6):C1346-54.
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von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex. J Thromb Haemost. 2004 Jan; 2(1):161-9.
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Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. J Cell Biol. 2003 Dec 08; 163(5):1033-44.
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Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Mol Genet Metab. 2003 Sep-Oct; 80(1-2):207-15.