"Cytochrome P-450 CYP1A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as CAFFEINE and ACETAMINOPHEN.
| Descriptor ID |
D019388
|
| MeSH Number(s) |
D08.244.453.005.443 D08.244.453.100.750 D08.811.682.690.708.170.010.443 D08.811.682.690.708.170.020.750 D12.776.422.220.453.010.443 D12.776.422.220.453.100.750
|
| Concept/Terms |
Cytochrome P-450 CYP1A2- Cytochrome P-450 CYP1A2
- CYP1A2, Cytochrome P-450
- Cytochrome P 450 CYP1A2
- Cytochrome P-450d
- Cytochrome P 450d
- Phenacetin O-Dealkylase
- O-Dealkylase, Phenacetin
- Phenacetin O Dealkylase
- Caffeine Demethylase
- Demethylase, Caffeine
- Cytochrome P-450 LM4
- Cytochrome P 450 LM4
- P-450 LM4, Cytochrome
- Cytochrome P450 1A2
- CYP1A2
- CYP 1A2
- Cytochrome P-450 LM(4)
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A2".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A2".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A2" by people in this website by year, and whether "Cytochrome P-450 CYP1A2" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2000 | 2 | 1 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2015 | 4 | 0 | 4 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1A2" by people in Profiles.
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Genetic variation in melatonin pathway enzymes in children with autism spectrum disorder and comorbid sleep onset delay. J Autism Dev Disord. 2015 Jan; 45(1):100-10.
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Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv(16)(p13.1q22); CBF?-MYH11. Int J Environ Res Public Health. 2012 08; 9(8):2788-800.
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Development of asymptomatic pancreatitis with paradoxically high serum clozapine levels in a patient with schizophrenia and the CYP1A2*1F/1F genotype. J Clin Psychopharmacol. 2010 Dec; 30(6):737-9.
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Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. Carcinogenesis. 2008 Jun; 29(6):1184-91.
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Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. Carcinogenesis. 2006 Jan; 27(1):103-11.
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Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury. J Pharmacol Exp Ther. 2004 Aug; 310(2):512-9.
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Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones. Drug Metab Dispos. 2003 Jul; 31(7):924-31.
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Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets. Carcinogenesis. 2000 Jun; 21(6):1157-62.