Item Type | Name |
Concept
|
Homeodomain Proteins
|
Concept
|
Archaeal Proteins
|
Concept
|
Membrane Transport Proteins
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Membrane Proteins
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Luminescent Proteins
|
Concept
|
Helminth Proteins
|
Concept
|
Chromosomal Proteins, Non-Histone
|
Concept
|
Carrier Proteins
|
Concept
|
Cell Cycle Proteins
|
Concept
|
Escherichia coli Proteins
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Eye Proteins
|
Concept
|
Bacterial Proteins
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Calcium-Binding Proteins
|
Concept
|
Bacterial Outer Membrane Proteins
|
Concept
|
Plant Proteins
|
Concept
|
Fungal Proteins
|
Concept
|
Saccharomyces cerevisiae Proteins
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
Iron-Sulfur Proteins
|
Concept
|
Nuclear Proteins
|
Concept
|
Recombinant Proteins
|
Concept
|
Neoplasm Proteins
|
Concept
|
Caenorhabditis elegans Proteins
|
Concept
|
Drosophila Proteins
|
Concept
|
Small Ubiquitin-Related Modifier Proteins
|
Concept
|
Ribosome Inactivating Proteins, Type 2
|
Concept
|
Mutant Proteins
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Arabidopsis Proteins
|
Concept
|
Apoptosis Regulatory Proteins
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Blood Proteins
|
Concept
|
Fimbriae Proteins
|
Concept
|
Tumor Suppressor Proteins
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Viral Proteins
|
Concept
|
Repressor Proteins
|
Concept
|
Xenopus Proteins
|
Concept
|
Schizosaccharomyces pombe Proteins
|
Concept
|
Proteins
|
Concept
|
Proto-Oncogene Proteins c-vav
|
Concept
|
Ribosome Inactivating Proteins
|
Academic Article
|
Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
|
Academic Article
|
Amino acid hydrophobicity in the context of folded proteins
|
Academic Article
|
Charging of Proteins in Native Mass Spectrometry
|
Academic Article
|
The interdependence of protein surface topography and bound water molecules revealed by surface accessibility and fractal density measures.
|
Academic Article
|
Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase.
|
Academic Article
|
The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles.
|
Academic Article
|
Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III.
|
Academic Article
|
Crystallization and crystallographic characterization of the iron-sulfur-containing DNA-repair enzyme endonuclease III from Escherichia coli.
|
Academic Article
|
Metal-binding sites in proteins.
|
Academic Article
|
Protein metal-binding sites.
|
Academic Article
|
Altering the antigenicity of proteins.
|
Academic Article
|
Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines.
|
Academic Article
|
Biochemical purification and crystallographic characterization of the fiber-forming protein pilin from Neisseria gonorrhoeae.
|
Academic Article
|
Elucidating the structural chemistry of glycosaminoglycan recognition by protein C inhibitor.
|
Academic Article
|
Visualization of molecular flexibility and its effects on electrostatic recognition.
|
Academic Article
|
Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.
|
Academic Article
|
Gonococcal pilus: genetics and structure.
|
Academic Article
|
Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene.
|
Academic Article
|
Evolution of CuZn superoxide dismutase and the Greek key beta-barrel structural motif.
|
Academic Article
|
Three dimensional structure of bacterial pili.
|
Academic Article
|
Understanding the structure and antigenicity of gonococcal pili.
|
Academic Article
|
Crystallographic structure of a photoreceptor protein at 2.4 A resolution.
|
Academic Article
|
Crystallographic characterization of recombinant human CuZn superoxide dismutase.
|
Academic Article
|
Recognition and interactions controlling the assemblies of beta barrel domains.
|
Academic Article
|
The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein.
|
Academic Article
|
Crystallization and preliminary crystallographic study of human CksHs1: a cell cycle regulatory protein.
|
Academic Article
|
Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis.
|
Academic Article
|
Structure of the fibre-forming protein pilin at 2.6 A resolution.
|
Academic Article
|
Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch.
|
Academic Article
|
Predicting molecular interactions and inducible complementarity: fragment docking of Fab-peptide complexes.
|
Academic Article
|
Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA.
|
Academic Article
|
Purification and crystallization of a schistosomal glutathione S-transferase.
|
Academic Article
|
Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1.
|
Academic Article
|
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
|
Academic Article
|
Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain.
|
Academic Article
|
The role of arginine 143 in the electrostatics and mechanism of Cu,Zn superoxide dismutase: computational and experimental evaluation by mutational analysis.
|
Academic Article
|
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.
|
Academic Article
|
DNA repair proteins.
|
Academic Article
|
Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel.
|
Academic Article
|
Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control.
|
Academic Article
|
Molecular recognition in DNA-binding proteins and enzymes.
|
Academic Article
|
Structure and function of Escherichia coli endonuclease III.
|
Academic Article
|
A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly.
|
Academic Article
|
Assembly and antigenicity of the Neisseria gonorrhoeae pilus mapped with antibodies.
|
Academic Article
|
Atomic and residue hydrophilicity in the context of folded protein structures.
|
Academic Article
|
Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase.
|
Academic Article
|
Rational design and expression of a heparin-targeted human superoxide dismutase.
|
Academic Article
|
Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1.
|
Academic Article
|
Consequences of the loss of O-linked glycosylation of meningococcal type IV pilin on piliation and pilus-mediated adhesion.
|
Academic Article
|
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
|
Academic Article
|
The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
|
Academic Article
|
Type-4 pilus-structure: outside to inside and top to bottom--a minireview.
|
Academic Article
|
Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human Cu,Zn superoxide dismutase.
|
Academic Article
|
Flap endonuclease homologs in archaebacteria exist as independent proteins.
|
Academic Article
|
Screening a peptidyl database for potential ligands to proteins with side-chain flexibility.
|
Academic Article
|
Purification and characterization of Thermotoga maritima endonuclease IV, a thermostable apurinic/apyrimidinic endonuclease and 3'-repair diesterase.
|
Academic Article
|
Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex.
|
Academic Article
|
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.
|
Academic Article
|
Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphology.
|
Academic Article
|
Interrupting the hydrogen bond network at the active site of human manganese superoxide dismutase.
|
Academic Article
|
Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.
|
Academic Article
|
Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase.
|
Academic Article
|
Structure of the DNA repair enzyme endonuclease IV and its DNA complex: double-nucleotide flipping at abasic sites and three-metal-ion catalysis.
|
Academic Article
|
DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected].
|
Academic Article
|
Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis.
|
Academic Article
|
Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding.
|
Academic Article
|
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily.
|
Academic Article
|
Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects.
|
Academic Article
|
Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine.
|
Academic Article
|
Crystal structure and novel recognition motif of rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis.
|
Academic Article
|
Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction.
|
Academic Article
|
N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.
|
Academic Article
|
The food of sweet and bitter fancy.
|
Academic Article
|
Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O(6)-alkylguanine-DNA alkyltransferase.
|
Academic Article
|
Lessons learned from structural results on uracil-DNA glycosylase.
|
Academic Article
|
Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means.
|
Academic Article
|
Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions.
|
Academic Article
|
DNA mismatch repair: the hands of a genome guardian.
|
Academic Article
|
Repair activities of 8-oxoguanine DNA glycosylase from Archaeoglobus fulgidus, a hyperthermophilic archaeon.
|
Academic Article
|
Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
|
Academic Article
|
Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication.
|
Academic Article
|
The pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease.
|
Academic Article
|
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
|
Academic Article
|
Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.
|
Academic Article
|
Structural chemistry of a green fluorescent protein Zn biosensor.
|
Academic Article
|
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
|
Academic Article
|
Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically inactive protein.
|
Academic Article
|
Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures.
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Academic Article
|
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2.
|
Academic Article
|
Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures.
|
Academic Article
|
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin.
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Academic Article
|
Identification of a new cryptochrome class. Structure, function, and evolution.
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Academic Article
|
Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase from Schistosoma japonicum.
|
Academic Article
|
The rad50 signature motif: essential to ATP binding and biological function.
|
Academic Article
|
Nickel superoxide dismutase structure and mechanism.
|
Academic Article
|
Structural and functional analysis of Mre11-3.
|
Academic Article
|
Type IV pilus structure and bacterial pathogenicity.
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Academic Article
|
Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair protein complex.
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Academic Article
|
Structure and function of the double-strand break repair machinery.
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Academic Article
|
The ATPase activity of BfpD is greatly enhanced by zinc and allosteric interactions with other Bfp proteins.
|
Academic Article
|
Understanding GFP chromophore biosynthesis: controlling backbone cyclization and modifying post-translational chemistry.
|
Academic Article
|
Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation.
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Academic Article
|
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome.
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Academic Article
|
A nanomachine for making ends meet: MRN is a flexing scaffold for the repair of DNA double-strand breaks.
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Academic Article
|
Protein mimicry of DNA and pathway regulation.
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Academic Article
|
Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2.
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Academic Article
|
Defining the role of arginine 96 in green fluorescent protein fluorophore biosynthesis.
|
Academic Article
|
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
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Academic Article
|
Understanding GFP posttranslational chemistry: structures of designed variants that achieve backbone fragmentation, hydrolysis, and decarboxylation.
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Academic Article
|
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair.
|
Academic Article
|
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions.
|
Academic Article
|
Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction.
|
Academic Article
|
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography.
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Academic Article
|
The case of the missing ring: radical cleavage of a carbon-carbon bond and implications for GFP chromophore biosynthesis.
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Academic Article
|
Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.
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Academic Article
|
Hexameric structures of the archaeal secretion ATPase GspE and implications for a universal secretion mechanism.
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Academic Article
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Learning our ABCs: Rad50 directs MRN repair functions via adenylate kinase activity from the conserved ATP binding cassette.
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Academic Article
|
The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
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Academic Article
|
Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications.
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Academic Article
|
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.
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Academic Article
|
DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy.
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Academic Article
|
Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease.
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Academic Article
|
SUMO-targeted ubiquitin ligases in genome stability.
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Academic Article
|
Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
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Academic Article
|
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.
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Academic Article
|
Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.
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Academic Article
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Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination.
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Academic Article
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XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations.
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Academic Article
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Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.
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Academic Article
|
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
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Academic Article
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The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.
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Academic Article
|
A SIM-ultaneous role for SUMO and ubiquitin.
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Academic Article
|
Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability.
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Academic Article
|
Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes.
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Academic Article
|
Molecular mimicry of SUMO promotes DNA repair.
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Academic Article
|
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair.
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Academic Article
|
A charged performance by gp17 in viral packaging.
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Academic Article
|
Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case.
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Academic Article
|
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS).
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Academic Article
|
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
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Academic Article
|
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex.
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Academic Article
|
Amyotrophic lateral sclerosis.
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Academic Article
|
Alkyltransferase-like proteins: molecular switches between DNA repair pathways.
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Academic Article
|
Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus-mediated microcolony formation.
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Academic Article
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Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states.
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Academic Article
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ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining.
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Academic Article
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gammaH2A binds Brc1 to maintain genome integrity during S-phase.
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Academic Article
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Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering.
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Academic Article
|
Structural dynamics in DNA damage signaling and repair.
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Academic Article
|
Microbial metalloproteomes are largely uncharacterized.
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Academic Article
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XLF regulates filament architecture of the XRCC4?ligase IV complex.
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Academic Article
|
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation.
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Academic Article
|
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks.
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Academic Article
|
ATP induces conformational changes in the carboxyl-terminal region of ClC-5.
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Academic Article
|
The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system.
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Academic Article
|
Mapping interactions between the RNA chaperone FinO and its RNA targets.
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Academic Article
|
Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding.
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Academic Article
|
Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law.
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Academic Article
|
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.
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Academic Article
|
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair.
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Academic Article
|
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
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Academic Article
|
DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes.
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Academic Article
|
The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome.
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Academic Article
|
P53 conformational switching for selectivity may reveal a general solution for specific DNA binding.
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Academic Article
|
A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data.
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Academic Article
|
SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability.
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Academic Article
|
All stressed out without ATM kinase.
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Academic Article
|
Ultrahigh resolution and full-length pilin structures with insights for filament assembly, pathogenic functions, and vaccine potential.
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Academic Article
|
DNA charge transport as a first step in coordinating the detection of lesions by repair proteins.
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Academic Article
|
Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants.
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Academic Article
|
Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase.
|
Academic Article
|
Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability.
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Academic Article
|
Structural tuning of the fluorescent protein iLOV for improved photostability.
|
Academic Article
|
Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.
|
Academic Article
|
Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems.
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Academic Article
|
Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
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Academic Article
|
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-p interactions.
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Academic Article
|
Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2.
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Academic Article
|
Developing advanced X-ray scattering methods combined with crystallography and computation.
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Academic Article
|
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
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Academic Article
|
Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB.
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Academic Article
|
XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.
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Academic Article
|
Super-resolution in solution X-ray scattering and its applications to structural systems biology.
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Academic Article
|
Accurate assessment of mass, models and resolution by small-angle scattering.
|
Academic Article
|
Comprehensive macromolecular conformations mapped by quantitative SAXS analyses.
|
Academic Article
|
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
|
Academic Article
|
Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics.
|
Academic Article
|
Probing DNA by 2-OG-dependent dioxygenase.
|
Academic Article
|
A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation.
|
Academic Article
|
ModBase, a database of annotated comparative protein structure models and associated resources.
|
Academic Article
|
Accurate SAXS profile computation and its assessment by contrast variation experiments.
|
Academic Article
|
Structural insights into the interaction of IL-33 with its receptors.
|
Academic Article
|
DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals.
|
Academic Article
|
Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.
|
Academic Article
|
DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.
|
Academic Article
|
The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.
|
Academic Article
|
A structure-specific nucleic acid-binding domain conserved among DNA repair proteins.
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Academic Article
|
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
|
Academic Article
|
Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins.
|
Academic Article
|
Intact functional fourteen-subunit respiratory membrane-bound [NiFe]-hydrogenase complex of the hyperthermophilic archaeon Pyrococcus furiosus.
|
Academic Article
|
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
|
Academic Article
|
RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.
|
Academic Article
|
The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures.
|
Academic Article
|
The Salmonella type III secretion system virulence effector forms a new hexameric chaperone assembly for export of effector/chaperone complexes.
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Academic Article
|
Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes.
|
Academic Article
|
Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair.
|
Academic Article
|
Emerging critical roles of Fe-S clusters in DNA replication and repair.
|
Academic Article
|
Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response.
|
Academic Article
|
FlaF Is a ?-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein.
|
Academic Article
|
Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining.
|
Academic Article
|
RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
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Academic Article
|
Exploring the repeat protein universe through computational protein design.
|
Academic Article
|
Perchlorate Reductase Is Distinguished by Active Site Aromatic Gate Residues.
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Academic Article
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The nucleotide-dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor.
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Academic Article
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FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles.
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Academic Article
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Noncoding RNA joins Ku and DNA-PKcs for DNA-break resistance in breast cancer.
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Academic Article
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HU multimerization shift controls nucleoid compaction.
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Academic Article
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Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.
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Academic Article
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Charging of Proteins in Native Mass Spectrometry.
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Academic Article
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The ATPase Motor Turns for Type IV Pilus Assembly.
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Academic Article
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Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
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Academic Article
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An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
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Academic Article
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MacroBac: New Technologies for Robust and Efficient Large-Scale Production of Recombinant Multiprotein Complexes.
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Academic Article
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Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.
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Academic Article
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Coiled coils unspring protein origami.
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Academic Article
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Uncovering the secrets of protein interactions with the DNA enforcing genomic stability.
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Academic Article
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2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.
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Academic Article
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Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy.
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Academic Article
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Robust Production, Crystallization, Structure Determination, and Analysis of [Fe-S] Proteins: Uncovering Control of Electron Shuttling and Gating in the Respiratory Metabolism of Molybdopterin Guanine Dinucleotide Enzymes.
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Academic Article
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High Resolution Distance Distributions Determined by X-Ray and Neutron Scattering.
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Academic Article
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Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
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Academic Article
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Dissection of DNA double-strand-break repair using novel single-molecule forceps.
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Academic Article
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The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
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Academic Article
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Structural Control of Nonnative Ligand Binding in Engineered Mutants of Phosphoenolpyruvate Carboxykinase.
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Academic Article
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Bending Forks and Wagging Dogs--It's about the DNA 3' Tail.
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Concept
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MutL Proteins
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Concept
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Poly-ADP-Ribose Binding Proteins
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Concept
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Ataxia Telangiectasia Mutated Proteins
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Academic Article
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Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
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Academic Article
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Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
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Academic Article
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SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.
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Academic Article
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Small angle X-ray scattering-assisted protein structure prediction in CASP13 and emergence of solution structure differences.
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Academic Article
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The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility.
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Academic Article
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Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.
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Academic Article
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Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development.
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Academic Article
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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
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Academic Article
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Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair.
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Academic Article
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Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease.
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Academic Article
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Mechanism of efficient double-strand break repair by a long non-coding RNA.
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Academic Article
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Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.
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Academic Article
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An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIa within a flexible DNA repair complex.
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Academic Article
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Autism-Associated Vigilin Depletion Impairs DNA Damage Repair.
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Academic Article
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X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology.
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Academic Article
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Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus.
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Academic Article
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EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.
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Academic Article
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Target highlights in CASP14: Analysis of models by structure providers.
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Academic Article
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Aberrant RNA methylation triggers recruitment of an alkylation repair complex.
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Academic Article
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Monitoring Nuclease Activity by X-Ray Scattering Interferometry Using Gold Nanoparticle-Conjugated DNA.
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Academic Article
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RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles.
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Academic Article
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Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
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