| Item Type | Name |
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Academic Article
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Mismatch repair gene expression and genetic instability in testicular germ cell tumor.
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Academic Article
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Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model.
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Academic Article
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Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinoma.
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Concept
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Proto-Oncogene Proteins c-sis
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Proto-Oncogene Proteins c-rel
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Concept
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Proto-Oncogene Proteins B-raf
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Proto-Oncogene Proteins pp60(c-src)
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Concept
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Proto-Oncogene Proteins c-jun
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Proto-Oncogene Proteins c-ret
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Concept
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Proto-Oncogene Proteins c-fos
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Concept
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Proto-Oncogene Proteins c-met
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Concept
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Proto-Oncogene Proteins
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proto-Oncogene Proteins c-yes
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Academic Article
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c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
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Academic Article
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ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.
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Academic Article
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Primary oncocytic adenocarcinomas of the lung: a clinicopathologic, immunohistochemical, and molecular biologic analysis of 16 cases.
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Academic Article
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Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.
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Academic Article
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High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
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Academic Article
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Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancer.
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Academic Article
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Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion.
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Academic Article
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Amplification of chromosomal segment 4q12 in non-small cell lung cancer.
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Academic Article
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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells.
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Academic Article
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Cotargeting cyclin D1 starts a new chapter in lung cancer prevention and therapy.
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Academic Article
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Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
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Academic Article
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Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.
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Academic Article
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Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
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Academic Article
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An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
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Academic Article
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The V599E BRAF mutation is uncommon in biliary tract cancers.
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Academic Article
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Microsatellite instability and loss of heterozygosity have distinct prognostic value for testicular germ cell tumor recurrence.
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Academic Article
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Lung premalignancy induced by mutant B-Raf, what is thy fate? To senesce or not to senesce, that is the question.
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Academic Article
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Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.
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Academic Article
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Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas.
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Academic Article
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Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence.
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Academic Article
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Pulmonary adenocarcinoma: a renewed entity in 2011.
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Academic Article
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Combined MEK and VEGFR inhibition in orthotopic human lung cancer models results in enhanced inhibition of tumor angiogenesis, growth, and metastasis.
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Academic Article
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Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
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Academic Article
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CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
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Academic Article
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[Gallbladder carcinoma: expression of the c-myc and ras-p-21 oncogene products].
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Academic Article
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Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
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Academic Article
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Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
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Academic Article
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KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer.
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Academic Article
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Phase II study of dasatinib in patients with advanced non-small-cell lung cancer.
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Academic Article
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STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma.
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Academic Article
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An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
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Academic Article
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Clinical and biomarker outcomes of the phase II vandetanib study from the BATTLE trial.
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Academic Article
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The relative expression of Mig6 and EGFR is associated with resistance to EGFR kinase inhibitors.
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Academic Article
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Elevated phospho-S6 expression is associated with metastasis in adenocarcinoma of the lung.
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Academic Article
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Integration of molecular profiling into the lung cancer clinic.
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Academic Article
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ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.
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Academic Article
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A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras.
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Academic Article
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High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation.
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Academic Article
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Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.
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Academic Article
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Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma.
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Academic Article
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Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.
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Academic Article
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ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.
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Academic Article
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Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience.
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Academic Article
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An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.
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Academic Article
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Multiplatform-based molecular subtypes of non-small-cell lung cancer.
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Academic Article
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Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis.
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Academic Article
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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
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Academic Article
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Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.
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Academic Article
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KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib.
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Academic Article
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Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations.
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Academic Article
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ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.
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Academic Article
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IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
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Academic Article
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Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
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Academic Article
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PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.
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Academic Article
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High prevalence of mutant KRAS in circulating exosome-derived DNA from early-stage pancreatic cancer patients.
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Academic Article
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XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
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Academic Article
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Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer.
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Academic Article
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CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
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Academic Article
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Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
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Academic Article
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Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.
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Academic Article
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Genomic Landscape of Atypical Adenomatous Hyperplasia Reveals Divergent Modes to Lung Adenocarcinoma.
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Academic Article
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The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer.
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Academic Article
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Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident.
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Academic Article
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STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.
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Academic Article
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Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
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Academic Article
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Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
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Academic Article
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PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.
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Academic Article
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Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.
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Academic Article
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ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.
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Academic Article
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YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.
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Academic Article
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Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance.
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Academic Article
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.
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Academic Article
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Interplay between estrogen and Stat3/NF-?B-driven immunomodulation in lung cancer.
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Academic Article
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Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion.
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Academic Article
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Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax.
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Academic Article
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Biomarker analyses from a placebo-controlled phase II study evaluating erlotinib?onartuzumab in advanced non-small cell lung cancer: MET expression levels are predictive of patient benefit.
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Academic Article
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PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer.
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Academic Article
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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T?cells.
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Academic Article
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Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.
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Academic Article
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An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
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