"Emetine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.
| Descriptor ID |
D004640
|
| MeSH Number(s) |
D03.132.316 D03.633.100.531.321
|
| Concept/Terms |
Emetine- Emetine
- Methylcephaeline
- Ipecine
|
Below are MeSH descriptors whose meaning is more general than "Emetine".
Below are MeSH descriptors whose meaning is more specific than "Emetine".
This graph shows the total number of publications written about "Emetine" by people in this website by year, and whether "Emetine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
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Below are the most recent publications written about "Emetine" by people in Profiles.
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Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia. Clin Exp Hypertens. 2008 Oct; 30(7):497-510.
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Long-term depression in the superior cervical ganglion of the rat. Brain Res. 2008 Oct 09; 1234:25-31.
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Characterization of MPP(+)-induced cell death in a dopaminergic neuronal cell line: role of macromolecule synthesis, cytosolic calcium, caspase, and Bcl-2-related proteins. Exp Neurol. 1999 Sep; 159(1):274-82.
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Giant miniature end-plate potentials at the untreated and emetine-treated frog neuromuscular junction. J Physiol. 1989 May; 412:475-91.
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Emetine increases giant miniature endplate potential population at the frog neuromuscular junction. Brain Res. 1988 May 03; 447(2):293-8.
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Effects of emetine and dehydroemetine at the frog neuromuscular junction. Eur J Pharmacol. 1987 Jun 19; 138(2):257-64.
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Effect of a protein synthetic inhibitor on in vivo estimates of protein synthesis in dogs. Am J Physiol. 1987 May; 252(5 Pt 1):E595-8.
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Active tumor cell resistance to human natural killer lymphocyte attack. Cancer Res. 1981 Jul; 41(7):2803-8.