"Colchicine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE).
| Descriptor ID |
D003078
|
| MeSH Number(s) |
D03.132.225
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Colchicine".
Below are MeSH descriptors whose meaning is more specific than "Colchicine".
This graph shows the total number of publications written about "Colchicine" by people in this website by year, and whether "Colchicine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2020 | 1 | 6 | 7 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Colchicine" by people in Profiles.
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Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an international randomised trial. Lancet. 2023 11 04; 402(10413):1627-1635.
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Rationale and design of the colchicine for the prevention of perioperative atrial fibrillation in patients undergoing major noncardiac thoracic surgery (COP-AF) trial. Am Heart J. 2023 05; 259:87-96.
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A microtubule-connexin-43 regulatory link suppresses arrhythmias and cardiac fibrosis in Duchenne muscular dystrophy mice. Am J Physiol Heart Circ Physiol. 2022 11 01; 323(5):H983-H995.
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Genome-wide CRISPR screen identifies MTA3 as an inducer of gemcitabine resistance in pancreatic ductal adenocarcinoma. Cancer Lett. 2022 11 01; 548:215864.
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Safety and Efficacy of Colchicine in Patients with Stable CAD and ACS: A Systematic Review and Meta-analysis. Am J Cardiovasc Drugs. 2021 Nov; 21(6):659-668.
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Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors. Bioorg Chem. 2020 12; 105:104447.
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Targeting Inflammation After Myocardial Infarction. Curr Cardiol Rep. 2020 08 08; 22(10):110.
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2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020 06; 72(6):879-895.
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Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group. Pediatr Rheumatol Online J. 2020 Apr 15; 18(1):31.
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Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia. J Nat Prod. 2020 04 24; 83(4):937-954.