"Isoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)
| Descriptor ID |
D007546
|
| MeSH Number(s) |
D03.633.100.531
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Isoquinolines".
Below are MeSH descriptors whose meaning is more specific than "Isoquinolines".
This graph shows the total number of publications written about "Isoquinolines" by people in this website by year, and whether "Isoquinolines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 3 | 2 | 5 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 3 | 3 |
| 1999 | 0 | 4 | 4 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 4 | 5 |
| 2006 | 1 | 5 | 6 |
| 2007 | 1 | 2 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 5 | 1 | 6 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
| 2024 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Isoquinolines" by people in Profiles.
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MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors. J Immunother Cancer. 2024 Sep 23; 12(9).
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Tenapanor as Therapy for Hyperphosphatemia in Maintenance Dialysis Patients: Results from the OPTIMIZE Study. Kidney360. 2024 May 01; 5(5):732-742.
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Cardiovascular Safety of Roxadustat in CKD Anemia: A Fig Leaf Named Noninferiority. Clin J Am Soc Nephrol. 2021 08; 16(8):1155-1157.
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Fixed-Dose Netupitant and Palonosetron for Chronic Nausea in Cancer Patients: A Double-Blind, Placebo Run-in Pilot Randomized Clinical Trial. J Pain Symptom Manage. 2021 08; 62(2):223-232.e1.
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A dose-ranging study of the inhaled dual phosphodiesterase 3 and 4 inhibitor ensifentrine in COPD. Respir Res. 2020 Feb 10; 21(1):47.
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Unexpected Mutations in HIV-1 That Confer Resistance to the Tat Inhibitor Didehydro-Cortistatin A. mBio. 2019 07 09; 10(4).
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PRMT1 loss sensitizes cells to PRMT5 inhibition. Nucleic Acids Res. 2019 06 04; 47(10):5038-5048.
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Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019 05 01; 79(9):2327-2338.
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Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice. J Neuroinflammation. 2019 Apr 02; 16(1):69.
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Duvelisib, an oral dual PI3K-d,? inhibitor, shows clinical and pharmacodynamic activity in chronic lymphocytic leukemia and small lymphocytic lymphoma in a phase 1 study. Am J Hematol. 2018 11; 93(11):1318-1326.