Protein Tyrosine Phosphatase, Non-Receptor Type 1
"Protein Tyrosine Phosphatase, Non-Receptor Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
| Descriptor ID |
D054562
|
| MeSH Number(s) |
D08.811.277.352.650.775.300.100 D12.644.360.585.100 D12.776.476.564.100
|
| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 1- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatase, Non Receptor Type 1
- PTPase HA2
- Protein Tyrosine Phosphatase 1B
- PTPase 1B
- Protein-Tyrosine Phosphatase HA2
- Protein Tyrosine Phosphatase HA2
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 1".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 1" by people in Profiles.
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[Prescription of Jingdan Yimin for treatment of metabolic syndrome]. Zhongguo Zhong Yao Za Zhi. 2016 Jan; 41(2):272-278.
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Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis. J Clin Invest. 2013 Dec; 123(12):5082-97.
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Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing. J Biol Chem. 2013 Jun 14; 288(24):17675-88.
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Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):19226-31.
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Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure. Am J Physiol Endocrinol Metab. 2011 Jun; 300(6):E1002-11.
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Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin aIIb?3 to fibrinogen. J Biol Chem. 2010 Sep 17; 285(38):29059-68.
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Redox regulation of interleukin-4 signaling. Immunity. 2008 Oct 17; 29(4):551-64.
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Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations. Arthritis Rheum. 2005 Jul; 52(7):1993-8.
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A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet. 2004 Aug; 75(2):330-7.
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Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J Cardiovasc Pharmacol. 2004 May; 43(5):677-84.