Protein Tyrosine Phosphatase, Non-Receptor Type 11
"Protein Tyrosine Phosphatase, Non-Receptor Type 11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME.
| Descriptor ID |
D054592
|
| MeSH Number(s) |
D08.811.277.352.650.775.300.800 D08.811.277.352.650.775.700.800 D12.644.360.585.800 D12.776.476.564.800 D12.776.476.800.800
|
| Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 11- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Protein Tyrosine Phosphatase, Non Receptor Type 11
- SHPTP2
- Phosphotyrosine Phosphatase Syp
- SHP-2 Protein-Tyrosine Phosphatase
- Protein Tyrosine Phosphatase PTP3
- Shp-2 Tyrosine Phosphatase
- Shp 2 Tyrosine Phosphatase
- Tyrosine Phosphatase, Shp-2
- SHP2 Phosphatase
- Phosphatase, SHP2
- Protein-Tyrosine-Phosphatase 2C
- Protein Tyrosine Phosphatase 2C
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 11".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Hydrolases [D08.811.277]
- Esterases [D08.811.277.352]
- Phosphoric Monoester Hydrolases [D08.811.277.352.650]
- Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
- Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D08.811.277.352.650.775.300.800]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D08.811.277.352.650.775.700]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D08.811.277.352.650.775.700.800]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.644.360.585]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.644.360.585.800]
- Proteins [D12.776]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Protein Tyrosine Phosphatases, Non-Receptor [D12.776.476.564]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.776.476.564.800]
- SH2 Domain-Containing Protein Tyrosine Phosphatases [D12.776.476.800]
- Protein Tyrosine Phosphatase, Non-Receptor Type 11 [D12.776.476.800.800]
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 11".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 11" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 11" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 11" by people in Profiles.
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Transient abnormal lymphomyelopoiesis in a newborn with PTPN11 mutation associated Noonan syndrome. Cytometry B Clin Cytom. 2022 09; 102(5):409-411.
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Targeted Degradation of the Oncogenic Phosphatase SHP2. Biochemistry. 2021 08 31; 60(34):2593-2609.
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Proteogenomic and metabolomic characterization of human glioblastoma. Cancer Cell. 2021 04 12; 39(4):509-528.e20.
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Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment. Cancer Res. 2020 07 01; 80(13):2889-2902.
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Cardiac transplantation in children with Noonan syndrome. Pediatr Transplant. 2019 09; 23(6):e13535.
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Nuclear Shp2 directs normal embryo implantation via facilitating the ERa tyrosine phosphorylation by the Src kinase. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):4816-4821.
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Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity. J Cell Biol. 2013 Feb 18; 200(4):493-504.
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Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul; 31(14):2973-83.
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HERV-mediated genomic rearrangement of EYA1 in an individual with branchio-oto-renal syndrome. Am J Med Genet A. 2010 Nov; 152A(11):2854-60.
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PTPN11 mutation associated with aortic dilation and hypertrophic cardiomyopathy in a pediatric patient with Noonan syndrome. Pediatr Cardiol. 2010 Jan; 31(1):114-6.