"Carboxylesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
| Descriptor ID |
D043182
|
| MeSH Number(s) |
D08.811.277.352.100.100
|
| Concept/Terms |
Carboxylesterase- Carboxylesterase
- Isocarboxazid amidase
- amidase, Isocarboxazid
- Non-specific Esterase
- Esterase, Non-specific
- Non specific Esterase
- Nonspecific Esterase
- Esterase, Nonspecific
- Procaine Esterase
- Esterase, Procaine
- Ali-esterase
- Ali esterase
- B-esterase
- B esterase
- CAP-hydrolyzing Enzyme
- CAP hydrolyzing Enzyme
- Enzyme, CAP-hydrolyzing
- Capsaicin-Hydrolyzing Enzyme
- Capsaicin Hydrolyzing Enzyme
- Enzyme, Capsaicin-Hydrolyzing
- Carboxyesterase
- Carboxylate Esterase
- Esterase, Carboxylate
- Carboxylester Lipase
- Lipase, Carboxylester
- Carboxylesterase B
- Carboxylic Ester Hydrolase
- Ester Hydrolase, Carboxylic
- Hydrolase, Carboxylic Ester
- Naproxen Esterase
- Esterase, Naproxen
- Non-specific Carboxylesterase
- Carboxylesterase, Non-specific
- Non specific Carboxylesterase
|
Below are MeSH descriptors whose meaning is more general than "Carboxylesterase".
Below are MeSH descriptors whose meaning is more specific than "Carboxylesterase".
This graph shows the total number of publications written about "Carboxylesterase" by people in this website by year, and whether "Carboxylesterase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Carboxylesterase" by people in Profiles.
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CES2 sustains HNF4a expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop. Mol Metab. 2022 02; 56:101426.
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Structure-guided microbial targeting of antistaphylococcal prodrugs. Elife. 2021 07 19; 10.
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Impact of diet on irinotecan toxicity in mice. Chem Biol Interact. 2018 Aug 01; 291:87-94.
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Role of Toll-like receptor 4 in drug-drug interaction between paclitaxel and irinotecan in vitro. Toxicol In Vitro. 2017 Jun; 41:75-82.
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Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer. PLoS One. 2016; 11(3):e0152300.
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Impact of obesity on accumulation of the toxic irinotecan metabolite, SN-38, in mice. Life Sci. 2015 Oct 15; 139:132-8.
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Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma. J Natl Cancer Inst. 2015 Aug; 107(8).
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Genetically-engineered human neural stem cells with rabbit carboxyl esterase can target CNS lymphoma. Anticancer Res. 2013 Dec; 33(12):5335-42.
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A1-3 chromosomal translocations in Italian populations of the peach potato aphid Myzus persicae (Sulzer) not linked to esterase-based insecticide resistance. Bull Entomol Res. 2013 Jun; 103(3):278-85.
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Genetically engineered human neural stem cells with rabbit carboxyl esterase can target brain metastasis from breast cancer. Cancer Lett. 2011 Dec 08; 311(2):152-9.