"Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.
| Descriptor ID |
D008049
|
| MeSH Number(s) |
D08.811.277.352.100.400
|
| Concept/Terms |
Lipase- Lipase
- Triacylglycerol Lipase
- Triolean Hydrolase
- Hydrolase, Triolean
- Triglyceridase
- Triglyceride Lipase
- Lipase, Triglyceride
- Triacylglycerol Hydrolase
- Hydrolase, Triacylglycerol
- Tributyrinase
|
Below are MeSH descriptors whose meaning is more general than "Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipase".
This graph shows the total number of publications written about "Lipase" by people in this website by year, and whether "Lipase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipase" by people in Profiles.
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PNPLA3, Obesity, and Heavy Alcohol Use in Cirrhosis Patients May Exert a Synergistic Increase Hepatocellular Carcinoma Risk. Clin Gastroenterol Hepatol. 2024 Sep; 22(9):1858-1866.e4.
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Structure-based virtual screening to identify potential lipase inhibitors to reduce lipid storage in Wolman disorder. Adv Protein Chem Struct Biol. 2023; 133:351-363.
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Metabolic liver disease - what's in a name? Nat Rev Endocrinol. 2021 02; 17(2):79-80.
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An Epistatic Interaction between Pnpla2 and Lipe Reveals New Pathways of Adipose Tissue Lipolysis. Cells. 2019 04 29; 8(5).
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Genetic Determinants of Circulating Lipoproteins in Nonalcoholic Fatty Liver Disease. J Clin Gastroenterol. 2018 May/Jun; 52(5):444-451.
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Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans. Science. 2015 Jan 02; 347(6217):83-6.
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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014 Feb 06; 94(2):233-45.
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Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: risk and prognosis prediction. Mol Carcinog. 2013 Nov; 52 Suppl 1:E139-47.
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Characteristics of patients with ketosis-prone diabetes (KPD) presenting with acute pancreatitis: implications for the natural history and etiology of a KPD subgroup. Endocr Pract. 2013 Mar-Apr; 19(2):243-51.
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Prognostic value of LIPC in non-small cell lung carcinoma. Cell Cycle. 2013 Feb 15; 12(4):647-54.