Interleukin-15 Receptor alpha Subunit
"Interleukin-15 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low affinity interleukin-15 receptor subunit that combines with the INTERLEUKIN-2 RECEPTOR BETA SUBUNIT and the INTERLEUKIN RECEPTOR COMMON GAMMA-CHAIN to form a high affinity receptor for INTERLEUKIN-15.
| Descriptor ID |
D053720
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.800.550
|
| Concept/Terms |
Interleukin-15 Receptor alpha Subunit- Interleukin-15 Receptor alpha Subunit
- Interleukin 15 Receptor alpha Subunit
- IL-15R alpha
- IL 15R alpha
- alpha, IL-15R
- Interleukin-15 Receptor alpha
- Interleukin 15 Receptor alpha
- Receptor alpha, Interleukin-15
- alpha, Interleukin-15 Receptor
- alpha-Subunit, Receptor, Interleukin-15
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-15 Receptor alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-15 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-15 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-15 Receptor alpha Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-15 Receptor alpha Subunit" by people in Profiles.
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NKTR-255 is a polymer-conjugated IL-15 with unique mechanisms of action on T and natural killer cells. J Clin Invest. 2021 10 01; 131(19).
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Lung Dendritic Cells Drive Natural Killer Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Ra. Am J Respir Crit Care Med. 2018 11 01; 198(9):1140-1150.
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Augmented IL-15Ra expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice. J Immunol. 2012 Jun 15; 188(12):6156-64.
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Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation. Blood. 2010 Oct 07; 116(14):2494-503.
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Differential mechanisms of memory CD8 T cell maintenance by individual myeloid cell types. J Leukoc Biol. 2010 Jul; 88(1):69-78.
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Trans-presentation of IL-15 by intestinal epithelial cells drives development of CD8alphaalpha IELs. J Immunol. 2009 Jul 15; 183(2):1044-54.
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Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentation. Blood. 2008 Dec 01; 112(12):4546-54.