Interleukin Receptor Common gamma Subunit
"Interleukin Receptor Common gamma Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interleukin receptor subunit that was originally discovered as a component of the INTERLEUKIN 2 RECEPTOR. It was subsequently found to be a component of several other receptors including the INTERLEUKIN 4 RECEPTOR, the INTERLEUKIN 7 RECEPTOR, the INTERLEUKIN-9 RECEPTOR, the INTERLEUKIN-15 RECEPTOR, and the INTERLEUKIN-21 RECEPTOR. Mutations in the gene for the interleukin receptor common gamma chain have been associated with X-LINKED COMBINED IMMUNODEFICIENCY DISEASES.
| Descriptor ID |
D053631
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.320.875 D12.776.543.750.705.852.420.360.300.500 D12.776.543.750.705.852.420.420.500 D12.776.543.750.705.852.420.500.500 D12.776.543.750.705.852.420.800.750 D12.776.543.750.705.852.420.900.500
|
| Concept/Terms |
Interleukin Receptor Common gamma Subunit- Interleukin Receptor Common gamma Subunit
- Interleukin-7 Receptor gamma Subunit
- Interleukin 7 Receptor gamma Subunit
- CD132 Antigen
- Antigen, CD132
- Antigens, CD132
- CD132 Antigens
- Interleukin-2 Receptor gamma Chain
- Interleukin 2 Receptor gamma Chain
- Interleukin-4 Receptor gamma Chain
- Interleukin 4 Receptor gamma Chain
- Interleukin-7 Receptor gamma Chain
- Interleukin 7 Receptor gamma Chain
- Interleukin-15 Receptor gamma Chain
- Interleukin 15 Receptor gamma Chain
- Interleukin-21 Receptor gamma Chain
- Interleukin 21 Receptor gamma Chain
- Interleukin Receptor Common gamma-Chain
- Interleukin Receptor Common gamma Chain
- Common Cytokine Receptor gamma Subunit
- Receptors, Interleukin Common gamma Chain
- Interleukin-15 Receptor gamma Subunit
- Interleukin 15 Receptor gamma Subunit
- Interleukin-2 Receptor gamma Subunit
- Interleukin 2 Receptor gamma Subunit
- Interleukin-21 Receptor gamma Subunit
- Interleukin 21 Receptor gamma Subunit
- Interleukin-4 Receptor gamma Subunit
- Interleukin 4 Receptor gamma Subunit
- Common gamma-Chain Protein
- Common gamma Chain Protein
- gamma-Chain Protein, Common
- Cytokine Receptor Common gamma Chain
|
Below are MeSH descriptors whose meaning is more general than "Interleukin Receptor Common gamma Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-2 [D12.776.543.750.705.852.420.320]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.320.875]
- Receptors, Interleukin-4 [D12.776.543.750.705.852.420.360]
- Receptors, Interleukin-4, Type I [D12.776.543.750.705.852.420.360.300]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.360.300.500]
- Receptors, Interleukin-7 [D12.776.543.750.705.852.420.420]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.420.500]
- Receptors, Interleukin-9 [D12.776.543.750.705.852.420.500]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.500.500]
- Receptors, Interleukin-15 [D12.776.543.750.705.852.420.800]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.800.750]
- Receptors, Interleukin-21 [D12.776.543.750.705.852.420.900]
- Interleukin Receptor Common gamma Subunit [D12.776.543.750.705.852.420.900.500]
Below are MeSH descriptors whose meaning is more specific than "Interleukin Receptor Common gamma Subunit".
This graph shows the total number of publications written about "Interleukin Receptor Common gamma Subunit" by people in this website by year, and whether "Interleukin Receptor Common gamma Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Interleukin Receptor Common gamma Subunit" by people in Profiles.
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The ClinGen Severe Combined Immunodeficiency Disease Variant Curation Expert Panel: Specifications for classification of variants in ADA, DCLRE1C, IL2RG, IL7R, JAK3, RAG1, and RAG2. Genet Med. 2026 Jan; 28(1):101613.
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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program. Nature. 2022 10; 610(7930):173-181.
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Linking newborn severe combined immunodeficiency screening with targeted exome sequencing: A case report. J Allergy Clin Immunol Pract. 2017 Sep - Oct; 5(5):1442-1444.
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Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma. Oncogene. 2015 Jul; 34(29):3770-9.
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Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia. Blood. 2014 Aug 28; 124(9):1460-72.
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Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. J Allergy Clin Immunol. 2014 Apr; 133(4):1109-15.
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Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity. PLoS One. 2013; 8(10):e76781.
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Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease. Haematologica. 2013 Apr; 98(4):533-7.
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MET signaling regulates glioblastoma stem cells. Cancer Res. 2012 Aug 01; 72(15):3828-38.
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Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment. Blood. 2012 May 24; 119(21):4971-80.