MAP Kinase Kinase Kinase 2
"MAP Kinase Kinase Kinase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 70-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 5. It is activated during the cellular response to GROWTH FACTORS, oxidative stress, and hyperosmotic conditions.
| Descriptor ID |
D048730
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.559.200 D12.644.360.400.200 D12.776.476.400.200
|
| Concept/Terms |
MAP Kinase Kinase Kinase 2- MAP Kinase Kinase Kinase 2
- MEKK-2 Protein Kinase
- MEKK 2 Protein Kinase
- Protein Kinase, MEKK-2
- MEKK2 Protein Kinase
- Protein Kinase, MEKK2
- MAP3K2 Protein Kinase
- Protein Kinase, MAP3K2
- MEKK2 Protein
- MEK Kinase 2
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 2".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 2".
This graph shows the total number of publications written about "MAP Kinase Kinase Kinase 2" by people in this website by year, and whether "MAP Kinase Kinase Kinase 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "MAP Kinase Kinase Kinase 2" by people in Profiles.
-
Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. Oncogene. 2021 03; 40(11):2081-2095.
-
An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing. PLoS Pathog. 2020 02; 16(2):e1008307.
-
Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways. EMBO J. 2006 Jan 11; 25(1):97-107.
-
MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. J Biol Chem. 2001 May 04; 276(18):14784-90.
-
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol Cell Biol. 2000 Apr; 20(7):2334-42.