MAP Kinase Kinase Kinase 5
"MAP Kinase Kinase Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE 4; and MAP KINASE KINASE 6.
| Descriptor ID |
D048848
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.559.500 D12.644.360.400.500 D12.776.476.400.500
|
| Concept/Terms |
MAP Kinase Kinase Kinase 5- MAP Kinase Kinase Kinase 5
- Apoptosis Signal-Regulating Kinase 1
- Apoptosis Signal Regulating Kinase 1
- MAPK Kinase Kinase 5
- MAP3K5 Protein Kinase
- Protein Kinase, MAP3K5
- Mitogen-Activated Kinase Kinase Kinase Kinase 5
- Mitogen Activated Kinase Kinase Kinase Kinase 5
- ASK1 Protein Kinase
- Protein Kinase, ASK1
- MAPKKK5
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase Kinase 5".
This graph shows the total number of publications written about "MAP Kinase Kinase Kinase 5" by people in this website by year, and whether "MAP Kinase Kinase Kinase 5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "MAP Kinase Kinase Kinase 5" by people in Profiles.
-
Genetic variation in the TNF/TRAF2/ASK1/p38 kinase signaling pathway as markers for postoperative pulmonary complications in lung cancer patients. Sci Rep. 2015 Jul 13; 5:12068.
-
Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin. J Invest Dermatol. 2014 Feb; 134(2):452-460.
-
Effects of butyltins on mitogen-activated-protein kinase kinase kinase and Ras activity in human natural killer cells. J Appl Toxicol. 2014 Sep; 34(9):1002-11.
-
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nat Genet. 2011 Dec 25; 44(2):165-9.
-
Genetic and biologic evidence that implicates a gene in aggressive prostate cancer. J Natl Cancer Inst. 2007 Dec 19; 99(24):1823-4.
-
TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway. Arterioscler Thromb Vasc Biol. 2007 Aug; 27(8):1760-7.
-
Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol. 2006 Oct 09; 175(1):121-33.
-
Neonatal vulnerability to ischemia and reperfusion: Cardioplegic arrest causes greater myocardial apoptosis in neonatal lambs than in mature lambs. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):490-7.
-
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science. 2000 Nov 24; 290(5496):1574-7.