"Ubiquitination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The act of ligating UBIQUITINS to PROTEINS to form ubiquitin-protein ligase complexes to label proteins for transport to the PROTEASOME ENDOPEPTIDASE COMPLEX where proteolysis occurs.
| Descriptor ID |
D054875
|
| MeSH Number(s) |
G02.111.660.871.790.600.925 G02.111.691.600.775 G03.734.871.790.600.831 G05.308.670.600.831
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitination".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitination".
This graph shows the total number of publications written about "Ubiquitination" by people in this website by year, and whether "Ubiquitination" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 3 | 3 |
| 2009 | 2 | 5 | 7 |
| 2010 | 1 | 6 | 7 |
| 2011 | 1 | 6 | 7 |
| 2012 | 0 | 7 | 7 |
| 2013 | 0 | 7 | 7 |
| 2014 | 2 | 2 | 4 |
| 2015 | 2 | 5 | 7 |
| 2016 | 0 | 3 | 3 |
| 2017 | 4 | 3 | 7 |
| 2018 | 4 | 9 | 13 |
| 2019 | 1 | 8 | 9 |
| 2020 | 1 | 6 | 7 |
| 2021 | 2 | 4 | 6 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 4 | 4 |
| 2024 | 1 | 2 | 3 |
| 2025 | 1 | 1 | 2 |
| 2026 | 1 | 3 | 4 |
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Below are the most recent publications written about "Ubiquitination" by people in Profiles.
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Bendless-mediated K63 ubiquitination modulates cellular signalling to regulate Drosophila hematopoiesis. Cell Commun Signal. 2026 Apr 22; 24(1).
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Loss of ZNRF3/RNF43 unleashes EGFR in cancer. Elife. 2026 Apr 10; 13.
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TFEB degradation is regulated by an IKK/?-TrCP2 phosphorylation-ubiquitination cascade. Nat Commun. 2026 04 01; 17(1).
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Ubiquitination of Oncogenic Mutant p53 via Attenuation of Ribosome Biogenesis Machinery Effectively Inhibits Pancreatic Tumor Growth. Mol Cancer Ther. 2026 Feb 04; 25(2):257-271.
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MYC-Targeting PROTACs Lead to Bimodal Degradation and N-Terminal Truncation. ACS Chem Biol. 2025 04 18; 20(4):896-906.
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Androgen receptor ubiquitination links KCTD13 to genitourinary tract defects. FASEB J. 2025 Feb 28; 39(4):e70406.
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PKC-mediated phosphorylation governs the stability and function of CELF1 as a driver of EMT in breast epithelial cells. J Biol Chem. 2024 11; 300(11):107826.
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Sphingosine kinase 2 regulates protein ubiquitination networks in neurons. Mol Cell Neurosci. 2024 Sep; 130:103948.
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Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases. Commun Biol. 2024 03 13; 7(1):321.
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SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells. Sci Transl Med. 2023 09 13; 15(713):eade2581.