"Protein Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The excision of in-frame internal protein sequences (INTEINS) of a precursor protein, coupled with ligation of the flanking sequences (EXTEINS). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein.
| Descriptor ID |
D019154
|
| MeSH Number(s) |
G02.111.660.871.790.600.700 G02.111.691.600.700 G03.734.871.790.600.700 G05.308.670.600.700
|
| Concept/Terms |
Protein Splicing- Protein Splicing
- Protein Splicings
- Splicing, Protein
- Splicings, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Splicing".
Below are MeSH descriptors whose meaning is more specific than "Protein Splicing".
This graph shows the total number of publications written about "Protein Splicing" by people in this website by year, and whether "Protein Splicing" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Splicing" by people in Profiles.
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The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Genes Dev. 2010 Jul 01; 24(13):1434-47.
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Structural insights into the protein splicing mechanism of PI-SceI. J Biol Chem. 2000 Jun 02; 275(22):16408-13.
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Differential effects of the widely expressed dMax splice variant of Max on E-box vs initiator element-mediated regulation by c-Myc. Oncogene. 1999 Apr 15; 18(15):2489-98.
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Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity. Cell. 1997 May 16; 89(4):555-64.