"Introns" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.
| Descriptor ID |
D007438
|
| MeSH Number(s) |
G05.360.340.024.220.400 G05.360.340.024.340.137.515
|
| Concept/Terms |
Introns- Introns
- Intron
- Sequences, Intervening
- Intervening Sequence
- Sequence, Intervening
- Intervening Sequences
|
Below are MeSH descriptors whose meaning is more general than "Introns".
Below are MeSH descriptors whose meaning is more specific than "Introns".
This graph shows the total number of publications written about "Introns" by people in this website by year, and whether "Introns" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 6 | 7 |
| 1996 | 1 | 7 | 8 |
| 1997 | 1 | 6 | 7 |
| 1998 | 2 | 13 | 15 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 10 | 10 |
| 2001 | 0 | 10 | 10 |
| 2002 | 3 | 6 | 9 |
| 2003 | 1 | 3 | 4 |
| 2004 | 1 | 9 | 10 |
| 2005 | 1 | 9 | 10 |
| 2006 | 0 | 6 | 6 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 6 | 7 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 6 | 7 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 5 | 5 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 4 | 5 |
| 2015 | 4 | 7 | 11 |
| 2016 | 0 | 7 | 7 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 7 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Introns" by people in Profiles.
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Reassessing the exon-foldon correspondence using frustration analysis. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2400151121.
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hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing. Mol Cell. 2024 Jun 06; 84(11):2087-2103.e8.
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A deep intronic recurrent CHEK2 variant c.1009-118_1009-87delinsC affects pre-mRNA splicing and contributes to hereditary breast cancer predisposition. Breast. 2024 Jun; 75:103721.
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Patterns of structural variants within TP53 introns and relocation of the TP53 promoter: a commentary?. J Pathol. 2024 06; 263(2):131-134.
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Validation and interpretation of Pan-TRK immunohistochemistry: a practical approach and challenges with interpretation. Diagn Pathol. 2024 Jan 10; 19(1):10.
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A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy. Mol Cell. 2023 07 06; 83(13):2258-2275.e11.
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Evidence-Based Guide to Using Artificial Introns for Tissue-Specific Knockout in Mice. Int J Mol Sci. 2023 Jun 17; 24(12).
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Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites. Sci Adv. 2023 02 17; 9(7):eade4814.
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Recurrent repeat expansions in human cancer genomes. Nature. 2023 01; 613(7942):96-102.
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Profiling human pathogenic repeat expansion regions by synergistic and multi-level impacts on molecular connections. Hum Genet. 2023 Feb; 142(2):245-274.