"Introns" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sequences of DNA in the genes that are located between the EXONS. They are transcribed along with the exons but are removed from the primary gene transcript by RNA SPLICING to leave mature RNA. Some introns code for separate genes.
| Descriptor ID |
D007438
|
| MeSH Number(s) |
G05.360.340.024.220.400 G05.360.340.024.340.137.515
|
| Concept/Terms |
Introns- Introns
- Intron
- Sequences, Intervening
- Intervening Sequence
- Sequence, Intervening
- Intervening Sequences
|
Below are MeSH descriptors whose meaning is more general than "Introns".
Below are MeSH descriptors whose meaning is more specific than "Introns".
This graph shows the total number of publications written about "Introns" by people in this website by year, and whether "Introns" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 6 | 7 |
| 1996 | 1 | 7 | 8 |
| 1997 | 1 | 6 | 7 |
| 1998 | 2 | 13 | 15 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 10 | 10 |
| 2001 | 0 | 11 | 11 |
| 2002 | 3 | 6 | 9 |
| 2003 | 1 | 3 | 4 |
| 2004 | 1 | 9 | 10 |
| 2005 | 1 | 9 | 10 |
| 2006 | 0 | 6 | 6 |
| 2007 | 2 | 2 | 4 |
| 2008 | 2 | 6 | 8 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 6 | 7 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 5 | 5 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 5 | 6 |
| 2015 | 4 | 7 | 11 |
| 2016 | 0 | 8 | 8 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 2 | 6 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Introns" by people in Profiles.
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Autoregulation of RPL7B by inhibition of a structural splicing enhancer. Nucleic Acids Res. 2025 Jul 19; 53(14).
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A deep intronic founder variant in the SERPINB7 gene causing aberrant splicing is a potential therapeutic target for Nagashima-type palmoplantar keratoderma. J Dermatol Sci. 2025 Aug; 119(2):73-81.
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Regulation of MCCC1 expression by a Parkinson's disease-associated intronic variant: implications for pathogenesis. J Hum Genet. 2025 Jul; 70(7):371-374.
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Reassessing the exon-foldon correspondence using frustration analysis. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2400151121.
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hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing. Mol Cell. 2024 Jun 06; 84(11):2087-2103.e8.
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A deep intronic recurrent CHEK2 variant c.1009-118_1009-87delinsC affects pre-mRNA splicing and contributes to hereditary breast cancer predisposition. Breast. 2024 Jun; 75:103721.
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Patterns of structural variants within TP53 introns and relocation of the TP53 promoter: a commentary?. J Pathol. 2024 06; 263(2):131-134.
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Validation and interpretation of Pan-TRK immunohistochemistry: a practical approach and challenges with interpretation. Diagn Pathol. 2024 Jan 10; 19(1):10.
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Genomic variants exclusively identified in children with birth defects and concurrent malignant tumors predispose to cancer development. Mol Cancer. 2023 08 05; 22(1):126.
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A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy. Mol Cell. 2023 07 06; 83(13):2258-2275.e11.