Large-Conductance Calcium-Activated Potassium Channels
"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
| Descriptor ID |
D051036
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| MeSH Number(s) |
D12.776.157.530.400.600.150.500 D12.776.543.550.450.750.150.500 D12.776.543.585.400.750.150.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 2 | 1 | 3 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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BK channel modulation by positively charged peptides and auxiliary ? subunits mediated by the Ca2+-bowl site. J Gen Physiol. 2023 06 05; 155(6).
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E-cigarette aerosols of propylene glycol impair BK channel activity and parameters of mucociliary function. Am J Physiol Lung Cell Mol Physiol. 2023 04 01; 324(4):L468-L479.
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SLO3 in the fast lane: The latest male contraceptive target with a promising small-molecule inhibitor. Proc Natl Acad Sci U S A. 2023 02 21; 120(8):e2221758120.
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The leucine-rich repeat domains of BK channel auxiliary ? subunits regulate their expression, trafficking, and channel-modulation functions. J Biol Chem. 2022 03; 298(3):101664.
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Glutamate-activated BK channel complexes formed with NMDA receptors. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):E9006-E9014.
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Molecular determinants of Ca2+ sensitivity at the intersubunit interface of the BK channel gating ring. Sci Rep. 2018 01 11; 8(1):509.
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Relationship between auxiliary gamma subunits and mallotoxin on BK channel modulation. Sci Rep. 2017 02 06; 7:42240.
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Closed state-coupled C-type inactivation in BK channels. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):6991-6.
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Presynaptic BK channels control transmitter release: physiological relevance and potential therapeutic implications. J Physiol. 2016 07 01; 594(13):3489-500.
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The single transmembrane segment determines the modulatory function of the BK channel auxiliary ? subunit. J Gen Physiol. 2016 Apr; 147(4):337-51.