Small-Conductance Calcium-Activated Potassium Channels
"Small-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium-activated potassium channels that are found primarily in excitable CELLS. They play important roles in the transmission of ACTION POTENTIALS and generate a long-lasting hyperpolarization known as the slow afterhyperpolarization.
| Descriptor ID |
D051640
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| MeSH Number(s) |
D12.776.157.530.400.600.150.750 D12.776.543.550.450.750.150.750 D12.776.543.585.400.750.150.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Small-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Small-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Small-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Variants in the SK2 channel gene (KCNN2) lead to dominant neurodevelopmental movement disorders. Brain. 2020 12 01; 143(12):3564-3573.
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A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism. Cell Rep. 2016 11 08; 17(7):1807-1818.
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Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery. J Am Heart Assoc. 2014 Aug 20; 3(4).
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Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog. Circulation. 2014 Jan 28; 129(4):430-40.
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Prenatal testosterone induces sex-specific dysfunction in endothelium-dependent relaxation pathways in adult male and female rats. Biol Reprod. 2013 Oct; 89(4):97.
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Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity. Cardiovasc Res. 2012 Sep 01; 95(4):439-47.
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Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4.
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Altered neurodevelopment associated with mutations of RSK2: a morphometric MRI study of Coffin-Lowry syndrome. Neurogenetics. 2007 Apr; 8(2):143-7.
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Regulation of surface localization of the small conductance Ca2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase. J Biol Chem. 2006 Apr 28; 281(17):11769-79.
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BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nat Neurosci. 2005 Dec; 8(12):1752-9.