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THOMAS GARCIA

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
AddressOne Baylor Plaza
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    Collapse Research 
    Collapse research activities and funding
    R01HD106056     (GARCIA, THOMAS)Feb 22, 2022 - Nov 30, 2026
    NIH
    Search for new genes involved in male infertility through novel approaches
    Role: Principal Investigator
    R01HD095341     (GARCIA, THOMAS)Apr 1, 2018 - Mar 31, 2021
    NIH
    FUNCTIONAL GENOMICS AND PROTEOMICS TO REVEAL REPRODUCTIVE-TRACT SPECIFIC PROTEINS
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Garcia TX, Matzuk MM. Novel Genes of the Male Reproductive System: Potential Roles in Male Reproduction and as Non-hormonal Male Contraceptive Targets. Mol Reprod Dev. 2024 10; 91(10):e70000. PMID: 39422082; PMCID: PMC12094158.
      Citations: 1     Fields:    Translation:HumansAnimals
    2. Parkes R, Garcia TX. Bringing proteomics to bear on male fertility: key lessons. Expert Rev Proteomics. 2024 Apr; 21(4):181-203. PMID: 38536015; PMCID: PMC11426281.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    3. Kent K, Nozawa K, Sutton C, Daniel F, Ikawa M, Garcia TX, Matzuk MM. CUB domains are not required for OVCH2 function in sperm maturation in the mouse epididymis. Andrology. 2024 Mar; 12(3):682-697. PMID: 37551853; PMCID: PMC10850435.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Sutton C, Nozawa K, Kent K, Saltzman A, Leng M, Nagarajan S, Malovannaya A, Ikawa M, Garcia TX, Matzuk MM. Molecular dissection and testing of PRSS37 function through LC-MS/MS and the generation of a PRSS37 humanized mouse model. Sci Rep. 2023 07 14; 13(1):11374. PMID: 37452050; PMCID: PMC10349139.
      Citations:    Fields:    Translation:HumansAnimals
    5. Tan Z, Garcia TX. SLO3 in the fast lane: The latest male contraceptive target with a promising small-molecule inhibitor. Proc Natl Acad Sci U S A. 2023 02 21; 120(8):e2221758120. PMID: 36791103; PMCID: PMC9974486.
      Citations:    Fields:    Translation:HumansCells
    6. Nozawa K, Garcia TX, Kent K, Leng M, Jain A, Malovannaya A, Yuan F, Yu Z, Ikawa M, Matzuk MM. Testis-specific serine kinase 3 is required for sperm morphogenesis and male fertility. Andrology. 2023 07; 11(5):826-839. PMID: 36306217; PMCID: PMC10267670.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    7. Nozawa K, Fujihara Y, Devlin DJ, Deras RE, Kent K, Larina IV, Umezu K, Yu Z, Sutton CM, Ye Q, Dean LK, Emori C, Ikawa M, Garcia TX, Matzuk MM. The testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice. BMC Biol. 2022 07 13; 20(1):161. PMID: 35831855; PMCID: PMC9277888.
      Citations:    Fields:    Translation:AnimalsCells
    8. Robertson MJ, Kent K, Tharp N, Nozawa K, Dean L, Mathew M, Grimm SL, Yu Z, Fujihara Y, Ikawa M, Coarfa C, Matzuk MM, Garcia TX, L?gar? C, Sullivan R. Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets. BMC Biol. 2020 08 19; 18(1):103. PMID: 32814578; PMCID: PMC7436996.
      Citations: 7     Fields:    Translation:HumansAnimals
    9. Kent K, Johnston M, Strump N, Garcia TX. Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets. Front Cell Dev Biol. 2020; 8:61. PMID: 32161754; PMCID: PMC7054227.
      Citations: 3     
    10. Holcomb RJ, Oura S, Nozawa K, Kent K, Yu Z, Robertson MJ, Coarfa C, Matzuk MM, Ikawa M, Garcia TX. The testis-specific serine proteases PRSS44, PRSS46, and PRSS54 are dispensable for male mouse fertility?. Biol Reprod. 2020 02 12; 102(1):84-91. PMID: 31403672; PMCID: PMC7013879.
      Citations: 20     Fields:    Translation:AnimalsCells
    11. Parekh PA, Garcia TX, Hofmann MC. Regulation of GDNF expression in Sertoli cells. Reproduction. 2019 03; 157(3):R95-R107. PMID: 30620720; PMCID: PMC6602878.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    12. Machol K, Rousseau J, Ehresmann S, Garcia T, Nguyen TTM, Spillmann RC, Sullivan JA, Shashi V, Jiang YH, Stong N, Fiala E, Willing M, Pfundt R, Kleefstra T, Cho MT, McLaughlin H, Roscioli T, Nixon CY, Buckley MF, Turner A, Jones WD, van Hasselt PM, Hofstede FC, van Gassen KLI, Brooks AS, van Slegtenhorst MA, Lachlan K, Sebastian J, Madan-Khetarpal S, Sonal D, Sakkubai N, Krantz ID, Tarpinian JM, Rosenfeld JA, Lee BH, Undiagnosed Diseases Network, Campeau PM, Rosello Piera M, Orellana C, Mart?nez F, Caro-Llopis A, Monfort S, Thevenon J, Faivre L, Maurel A, Petrovski S. Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay. Am J Hum Genet. 2019 01 03; 104(1):164-178. PMID: 30580808; PMCID: PMC6323608.
      Citations: 24     Fields:    Translation:Humans
    13. Garcia TX, Parekh P, Gandhi P, Sinha K, Hofmann MC. The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells. Stem Cells Dev. 2017 04 15; 26(8):585-598. PMID: 28051360; PMCID: PMC5393414.
      Citations: 26     Fields:    Translation:AnimalsCells
    14. Garcia TX, Farmaha JK, Kow S, Hofmann MC. RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. Development. 2014 Dec; 141(23):4468-78. PMID: 25406395; PMCID: PMC4302926.
      Citations: 27     Fields:    Translation:AnimalsCells
    15. Garcia TX, Costa GM, Hofmann MC, Fran?a LR. Sub-acute intravenous administration of silver nanoparticles in male mice alters Leydig cell function and testosterone levels. Reprod Toxicol. 2014 Jun; 45:59-70. PMID: 24447867; PMCID: PMC4309383.
      Citations: 18     Fields:    Translation:Animals
    16. Garcia TX, Hofmann MC. NOTCH signaling in Sertoli cells regulates gonocyte fate. Cell Cycle. 2013 Aug 15; 12(16):2538-45. PMID: 23907117; PMCID: PMC3865042.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
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